Does Vitamin D Deficiency Cause Hypertension? Current Evidence from Clinical Studies and Potential Mechanisms

Ullah, Mohammad; Uwaifo, Gabriel I.; Nicholas, W. Channing; Koch, Christian A.

doi:10.1155/2010/579640

Cited by 73 publications

(67 citation statements)

References 90 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several workers have reported that Vitamin D also has a role in blood pressure regulation and heart health [1,2]. Rostand [3] observed that cases of high blood pressure increase during winter and in the places that are far away from the equator, both are the situations where a decrease in available sunlight leads to lower Vitamin D production.…”

Section: Introductionmentioning

confidence: 99%

Role of Vitamin D Supplementation in Hypertension

Goel¹,

Lal²

2010

Ind J Clin Biochem

View full text Add to dashboard Cite

Role of Vitamin D supplementation was studied in patients with hypertension. One hundred hypertensive patients (group I) were given conventional antihypertensive drugs while another 100 patients (group II), in addition, were supplemented with Vitamin D 3 (33,000 IU, after every 2 weeks, for 3 months). Besides diastolic and systolic blood pressure, serum calcium, phosphorous, alkaline phosphatase, albumin, albumin-corrected calcium, and 24 h urinary creatinine levels were estimated in both the groups before the start of treatment and after 3 months. Vitamin D supplementation showed a more significant decrease in systolic blood pressure. This group also showed a significant increase in serum calcium as well as albumin-corrected calcium with a decrease in phosphorous. Results of the study confirm thfat Vitamin D supplementation has a role in reducing blood pressure in hypertensive patients and that it should be supplemented with the antihypertensive drugs. More extensive studies with a larger group, to draw a definite conclusion, are in progress.

show abstract

Section: Introductionmentioning

confidence: 99%

Role of Vitamin D Supplementation in Hypertension

Goel¹,

Lal²

2010

Ind J Clin Biochem

View full text Add to dashboard Cite

show abstract

“…35 Observational data are compelling, but not adequate for establishing causation. Because interactions between vitamin D, calcium, and parathyroid hormone are complex, separating the effects distinct to vitamin D in clinical trial can be difficult.…”

Section: Discussionmentioning

confidence: 99%

Effect of Serum Vitamin D Levels on Cardiovascular Mortality and Cardiovascular Disease Risk

Bennion

Luthy

Freeborn

et al. 2012

J Evid Based Complementary Altern Med

View full text Add to dashboard Cite

Vitamin D deficiency is prevalent across all geographic areas, age groups, and seasons and is increasing in incidence. Vitamin D receptors have been found to be present in almost every body cell and tissue. Clinical research has alluded to a preventive effect of vitamin D supplementation on cardiovascular disorders such as myocardial infarction, hypertension, and dyslipidemia. Furthermore, a low serum vitamin D level has been associated with an increased risk for cardiovascular disease. This article examines the association between serum vitamin D levels and cardiovascular disease mortality and risk.

show abstract

“…One similar study showed that people with higher levels of vitamin D had lower blood pressures and a lower risk of developing hypertension [14]. A review in 2013 looked at many studies involving people with hypertension.…”

Section: Association Of Low Vitamin D Levels and Hypertensionmentioning

confidence: 99%

Emergence of New Risk Factors for causing Hypertension

Team

2017

J Med Res Innov

View full text Add to dashboard Cite

The major risk factors which we have been hearing since decades for causing hypertension are high salt diet, obesity, hyperlipidaemia, age, race, consuming tobacco, sedentary lifestyle, stress, drinking too much alcohol etc. However, there are many studies which shows that sugar, fats and low vitamin d levels are equally responsible for causing hypertension. The article will put forward some interesting points to show that sugars, fats and vitamin d levels equally play an important role in causing hypertension.

show abstract

Does Vitamin D Deficiency Cause Hypertension? Current Evidence from Clinical Studies and Potential Mechanisms

Cited by 73 publications

References 90 publications

Role of Vitamin D Supplementation in Hypertension

Role of Vitamin D Supplementation in Hypertension

Effect of Serum Vitamin D Levels on Cardiovascular Mortality and Cardiovascular Disease Risk

Emergence of New Risk Factors for causing Hypertension

Contact Info

Product

Resources

About