Does water temperature influence the distribution and elimination of perfluorinated substances in rainbow trout (Oncorhynchus mykiss)?

Vidal, Alice; Lafay, Florent; Danièle, Gaëlle; Vulliet, Emmanuelle; Rochard, Éric; Garric, Jeanne; Babut, Marc

doi:10.1007/s11356-019-05029-w

Cited by 22 publications

(15 citation statements)

References 42 publications

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“…The PBTK model proposed here was calibrated using data from two dietary PFOS exposure experiments in rainbow trout conducted at different temperatures, i.e. 7°C and 19°C (methods and results are detailed in Vidal et al 2019a). Briefly, during 42d, adult rainbow trout were exposed to a diet spiked with a mixture of three PFAAs, including PFOS, at a nominal concentration of 500 ng g -1 (dry weight, dw).…”

Section: Model Calibrationmentioning

confidence: 99%

“…For each experiment, inputs to the model were the recorded water temperature and oxygen concentration, the mean initial fish length, the food amount provided and the PFOS amount administered (based on food amount) (see SI, Section A.2.). The predicted organ concentrations were fitted to the geometric mean of observed data (n=5) for the experiments conducted by Vidal et al (2019a).…”

Section: Model Calibrationmentioning

confidence: 99%

“…Jimenez et al (1987) showed in bluegill sunfish (Lepomis macrochirus) exposed to benzo(a)pyrene that uptake and elimination rates were lower at 13°C than at 23°C, and they went on to posit that water intake increases at warmer temperature, thereby increasing exposure. More recently, we showed that the distribution and elimination of selected perfluorinated alkyl substances (PFAAs) changed in rainbow trout exposed to the same concentration in food at different temperatures (Vidal et al, 2019a). PFAAs belong to the wider per-and polyfluorinated alkyl substances (PFAS) family, an important class of environmental contaminants with strong carbon-fluorine bonds that make them environmentally stable (Buck et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…However, these conclusions were drawn at a single exposure temperature. To push our analysis further, the next step was to study the influence of temperature on ADME processes using the same combination of experiments (Vidal et al 2019a) and modelling.…”

Section: Introductionmentioning

confidence: 99%

“…Modifications of physiological functions (fish growth, cardiac output, ventilation rate, organ perfusion) and PFOS kinetic processes (clearances, absorption rate, tissue-plasma partition coefficients) according to temperature were accounted for in the appropriate PBTK model functions. The PBTK model was developed and calibrated via a Bayesian approach using two datasets of PFOS concentrations in tissues of rainbow trout fed a PFOS-spiked diet, at 7°C and at 19°C (Vidal et al 2019a). Finally, model predictions were evaluated using an independent dataset in which mean water temperature was 15°C ).…”

Section: Introductionmentioning

confidence: 99%

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Temperature effect on perfluorooctane sulfonate toxicokinetics in rainbow trout (Oncorhynchus mykiss): Exploration via a physiologically based toxicokinetic model

et al. 2020

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Salmonids are poikilotherms which means that their internal temperature varies with that of water. Water temperature thus controls many of their lifecycle processes and physiological functions, which could influence the mechanisms of absorption, distribution, metabolism and excretion (ADME) of many substances, including perfluorinated alkyl substances (PFAAs). However, the processes governing the fate of PFAAs are still poorly understood in fish. Here we developed a physiologically based toxicokinetic (PBTK) model for rainbow trout (Oncorhynchus mykiss) to study changes in physiological functions and PFAA ADME at different temperatures. The model was calibrated using experimental data from dietary exposure to perfluorooctane sulfonate at 7°C and 19°C. Predictions of PFOS concentrations were globally satisfactory at both temperatures, when accounting for the influence of temperature on growth, ventilation rate, cardiac output, clearances, and absorption rates. Accounting for the influence of temperature on tissue-plasma partition coefficients significantly improved predicted inorgan PFOS concentrations.

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Section: Model Calibrationmentioning

confidence: 99%

Section: Model Calibrationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Temperature effect on perfluorooctane sulfonate toxicokinetics in rainbow trout (Oncorhynchus mykiss): Exploration via a physiologically based toxicokinetic model

et al. 2020

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A worldwide evaluation of trophic magnification of per‐ and polyfluoroalkyl substances in aquatic ecosystems

Miranda

Peaslee

Zachritz

et al. 2022

Integr Envir Assess & Manag

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A review of the published literature on the trophic magnification factor (TMF) for per-and polyfluoroalkyl substances (PFAS) was conducted to assess how biomagnification varies across aquatic systems worldwide. Although the TMF has been recognized as the most reliable tool for assessing the biomagnification of organic contaminants, peer-reviewed studies reporting TMFs for PFAS are few and with limited geographical distribution. We found 25 published studies of the biomagnification of 35 specific PFAS, for which the TMF was generated through linear regression of individual log-PFAS concentration and the δ 15 N-based trophic position of each organism in the food webs. Studies were concentrated mainly in China, North America, and Europe, and the most investigated compound was perfluorooctane sulfonate (PFOS), which was frequently shown to be biomagnified in the food web (TMFs ranging from 0.8 to 20). Other long-chain carboxylates displayed substantial variation in trophic magnification. Observed differences in the TMF were associated with length of the food web, geographic location, sampling methodologies, tissue analyzed, and distance from known direct PFAS inputs. In addition to biomagnification of legacy PFAS, precursor substances were observed to bioaccumulate in the food web, which suggests they may biotransform to more persistent PFAS compounds in upper trophic levels. This review discusses the variability of environmental characteristics driving PFAS biomagnification in natural ecosystems and highlights the different approaches used by each study, which can make comparisons among studies challenging. Suggestions on how to standardize TMFs for PFAS are also provided in this review.

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Predicting the dynamics of per- and polyfluoroalkyl substances in coastal regions of Africa: vulnerability index and adverse ecological pathways from remote-sensed variables

Chukwuka,

Adeogun

2024

Environ Monit Assess

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Does water temperature influence the distribution and elimination of perfluorinated substances in rainbow trout (Oncorhynchus mykiss)?

Cited by 22 publications

References 42 publications

Temperature effect on perfluorooctane sulfonate toxicokinetics in rainbow trout (Oncorhynchus mykiss): Exploration via a physiologically based toxicokinetic model

Temperature effect on perfluorooctane sulfonate toxicokinetics in rainbow trout (Oncorhynchus mykiss): Exploration via a physiologically based toxicokinetic model

A worldwide evaluation of trophic magnification of per‐ and polyfluoroalkyl substances in aquatic ecosystems

Predicting the dynamics of per- and polyfluoroalkyl substances in coastal regions of Africa: vulnerability index and adverse ecological pathways from remote-sensed variables

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