Obstructive sleep apnea (OSA) has been known to mankind since ancient times. Medical documents from 2000 years ago that have been found contain information describing severe snoring (apnea) characteristic of OSA. In order to obtain the information targeted research was carried out in the Scientific databases PubMed, Scopus, ScienceDirect, Web of Science. "History of OSA", "CPAP", "Polysomnography" keywords were used in for the search. The aim of this article is to present the historical development of methods for diagnosis and treatment of OSA. In 1981 Sullivan et al. published in the Lancet scientific paper on Obstructive Sleep Apnea " Reversal of obstructive sleep apnea by continuous air-way pressure applied through the nares " . At the end of the XIX th century, the term "Pickwickian syndrome" was introduced in the medical literature. In 1965, the polysomnographic unit was created and for the first time, with the help of electronic device, sleep apnea was registered in patients. Eventually ambulatory sleep testing was introduced as an alternative to polysomnography. Apnea Graph is a new innovative ambulatory sleep analysis tool that identifies the location of snoring obstruction and OSA. It also determines the type of OSA. In 1981, the first CPAP for treatment OSA was created. Sullivan's findings prove that CPAP is a very effective device for treating OSA.