Donkin psychosis

Brockington, Ian

doi:10.1007/s00737-016-0677-6

Cited by 6 publications

(3 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For patients who are 20 weeks or more of gestation, agitation may arise from obstetric-related conditions such as preeclampsia, placental abruption, or uterine contraction (Bijma et al, 2020; Niforatos et al, 2019). Patients with preeclampsia may manifest neurological features of altered mental status, severe headache, cerebral edema, acute cerebrovascular disorders, eclamptic seizures, and eclamptic psychoses (Brockington, 2017; Miller & Vollbracht, 2021). Agitation can also be attributable to intense pain from acute placental abruption and uterine contractions (Aftab & Shah, 2017; Bijma et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

An Obstetric and Psychiatric Emergency: Managing Acute Agitation Among Pregnant Patients in the Emergency Department

Woo,

Gantioque

2023

Advanced Emergency Nursing Journal

View full text Add to dashboard Cite

New onset of agitation during pregnancy is an obstetric and behavioral emergency that demands careful evaluation and prompt treatment. This article provides an overview of clinical evaluation and types of nonpharmacologic and pharmacologic interventions when managing acute agitation during pregnancy. Rapid clinical evaluation and behavioral management are keys to preventing detrimental maternal and fetal complications. Clinicians must seek out medical etiologies of agitation and always attempt verbal de-escalation before initiating chemical or physical restraints. Should medication be necessary, first-generation antipsychotics, second-generation antipsychotics, antihistamines, or benzodiazepines may be considered. Managing agitation in pregnancy is a challenging dilemma due to the fear of adverse maternal and neonatal outcomes as well as the legal risk involved. Nevertheless, clinicians should continue to assess the patient without delay, differentiate underlying causes of agitation, treat the mother and fetus aggressively, and consult obstetric and psychiatric services early.

show abstract

Section: Discussionmentioning

confidence: 99%

An Obstetric and Psychiatric Emergency: Managing Acute Agitation Among Pregnant Patients in the Emergency Department

Woo,

Gantioque

2023

Advanced Emergency Nursing Journal

View full text Add to dashboard Cite

show abstract

“…Second, immune disorders such as postpartum thyroiditis, rheumatoid arthritis and multiple sclerosis are typically exacerbated in the postpartum period, sharing similarities with the clinical course of postpartum psychosis [85]. Third, psychiatric symptoms resembling postpartum psychosis have been reported to occur in cases of im-munological disorders such as anti-N-methyl-D-aspartate receptor encephalitis [86] and pre-eclampsia [87], a disorder also linked with first pregnancies [88]. Notably, however, while a recent meta-analysis has shown pre-eclampsia to be associated with an increased severity of depressive symptoms in the postnatal period, no such relationship was observed with postpartum psychosis [89].…”

Section: Immunological Factorsmentioning

confidence: 99%

Phenomenology, Epidemiology and Aetiology of Postpartum Psychosis: A Review

et al. 2021

View full text Add to dashboard Cite

Postpartum psychoses are a severe form of postnatal mood disorders, affecting 1–2 in every 1000 deliveries. These episodes typically present as acute mania or depression with psychosis within the first few weeks of childbirth, which, as life-threatening psychiatric emergencies, can have a significant adverse impact on the mother, baby and wider family. The nosological status of postpartum psychosis remains contentious; however, evidence indicates most episodes to be manifestations of bipolar disorder and a vulnerability to a puerperal trigger. While childbirth appears to be a potent trigger of severe mood disorders, the precise mechanisms by which postpartum psychosis occurs are poorly understood. This review examines the current evidence with respect to potential aetiology and childbirth-related triggers of postpartum psychosis. Findings to date have implicated neurobiological factors, such as hormones, immunological dysregulation, circadian rhythm disruption and genetics, to be important in the pathogenesis of this disorder. Prediction models, informed by prospective cohort studies of high-risk women, are required to identify those at greatest risk of postpartum psychosis.

show abstract

“…Donkin Psychosis, first described by Arthur Donkin in 1863 9 is a specific form of pregnancy-associated psychosis and is also known as eclampsia psychosis without seizures (EPWS). Its etiology and pathophysiology are unclear, as is that of pre-eclampsia/eclampsia, although presumably they are related to similar factors: an impairment of the maternal immune system so that it fails to recognize the fetoplacental unit, chronic placental ischemia, widespread arteriolar endothelial dysfunction and spasm, elevated blood pressures, and thrombophilia1,10.…”

Section: Introductionmentioning

confidence: 99%