Dopaminergic and cholinergic stimulation of the ventrolateral striatum elicit rat jaw movements that are funnelled via distinct efferents

Adachi, Kazunori; Hasegawa, Megumi; Fujita, Satoshi; Sato, Michiko; Miwa, Yasuhiro; Ikeda, Hiroko; Koshikawa, Noriaki; Cools, Alexander R.

doi:10.1016/s0014-2999(02)01496-6

Cited by 23 publications

(5 citation statements)

References 35 publications

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“…The GPm is a major output pathway (along with substantia nigra reticulata) of the dorsal striatum, and it projects to the LHABm and motor thalamus in rats (Kha, Finkelstein, Pow, Lawrence, & Horne, 2000) and, at least in primates, to prefrontal and motor cortices (Middleton & Strick, 2002). The GPm is involved in limb movements (DeLong et al, 1984; Joel & Weiner, 1994) and jaw movements (Adachi et al, 2002), suggesting involvement in food handling and consummatory behaviors.…”

Section: Discussionmentioning

confidence: 99%

c-Fos After Incentive Shifts: Expectancy, Incredulity, and Recovery.

Pecoraro

Dallman

2005

Behavioral Neuroscience

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Rats were used in a successive negative contrast procedure to determine which brain structures were activated by sucrose concentration downshifts, and on what day this occurred. Subjects were given preshift solutions for 12 days before being shifted to their postshift concentrations. Groups included 2 unshifted controls (32%-32% and 4%-4%) and 1 shifted group (32%-4%). Half of each group was killed 1 hr after the first exposure to the shifted solution (Shift 1), and half after the second exposure (Shift 2). Brains were processed for c-Fos-like immunoreactivity (FLI). Two major patterns emerged. Terminal drinking of 32% sucrose activated minimal brainstem regions involved in palatable taste, visceral feedback, and fluid homeostasis. In contrast, shifted subjects showed extensive cortical activation with selective activation in cerebral nuclei and brainstem. Robust FLI on Shift 1 was absent on Shift 2, consistent with evidence for rapid (1-trial) changes in all major motor outputs mediated by expectancy.

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Section: Discussionmentioning

confidence: 99%

c-Fos After Incentive Shifts: Expectancy, Incredulity, and Recovery.

Pecoraro

Dallman

2005

Behavioral Neuroscience

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“…Masseter and digastric muscle-related jaw movements can be elicited by dopaminergic and cholinergic stimulation of several basal ganglia regions, including the striatum and substantia nigra zona reticulata (SNZR), a major efferent source of basal ganglia processing [80]. Orofaciolingual movements can be evoked by microstimulation and GABA microinjection of the SNZR in decorticate rats [81].…”

Section: Basal Ganglia Influence Over Oral Motor: Animal Studiesmentioning

confidence: 99%

Supranuclear Control of Swallowing

2009

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Swallowing is an act requiring complex sensorimotor integration. Using a variety of methods first used to study limb physiology, initial efforts to study swallowing have yielded information that multiple cortical and subcortical regions are active participants. Not surprisingly, the regions activated appear to overlap those involved in both oral and nonoral motor behaviors. This review offers a perspective that considers the supranuclear control of swallowing in light of these physiological similarities.

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“…[57] have also reported that intrastriatal administration of m -CPP induced purposeless oral movements that were abolished by the intrastriatal administration of mianserin. Interestingly, despite the role of the entopeduncular nucleus (EPN; the equivalent of the internal globus pallidus in primates) in mediating abnormal movements [58], stimulation of EPN 5-HT 2C receptors by the local administration of m -CPP did not stimulate bouts of oral movements [59]. On the other hand, high doses of m -CPP or TFMPP directly administered into the substantia nigra pars reticulata (SNr) have been shown to elicit abnormal oral movements [60].…”

Section: Introductionmentioning

confidence: 99%

Serotonin2C Receptors and the Motor Control of Oral Activity

Lagière

Navailles²,

Bosc³

et al. 2013

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Data from many experiments has shown that serotonin2C (5-HT2C) receptor plays a role in the control of orofacial activity in rodents. Purposeless oral movements can be elicited either by agonists or inverse agonists implying a tight control exerted by the receptor upon oral activity. The effects of agonists has been related to an action of these drugs in the subthalamic nucleus and the striatum, the two input structures for cortical efferents to the basal ganglia, a group of subcortical structures involved in the control of motor behaviors. The oral effects of agonists are dramatically enhanced in case of chronic blockade of central dopaminergic transmission induced by neuroleptics or massive destruction of dopamine neurons. The mechanisms involved in the hypersensitized oral responses to 5-HT2C agonists are not clear and deserve additional studies. Indeed, while the oral behavior triggered by 5-HT2C drugs would barely correspond to the dyskinesia observed in humans, the clinical data have consistently postulated that 5-HT2C receptors could be involved in these aberrant motor manifestations.

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Dopaminergic and cholinergic stimulation of the ventrolateral striatum elicit rat jaw movements that are funnelled via distinct efferents

Cited by 23 publications

References 35 publications

c-Fos After Incentive Shifts: Expectancy, Incredulity, and Recovery.

c-Fos After Incentive Shifts: Expectancy, Incredulity, and Recovery.

Supranuclear Control of Swallowing

Serotonin2C Receptors and the Motor Control of Oral Activity

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