Dose conversion coefficients for neutron exposure to the lens of the human eye

Manger, R; Bellamy, Michael; Eckerman, K.F.

doi:10.1093/rpd/ncr202

Cited by 22 publications

(48 citation statements)

References 4 publications

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“…Several scientific groups investigated the dose values for the lens for electrons (Behrens et al 2009;Behrens 2013;Nogueira et al 2011), photons (Behrens and Dietze 2010), and neutrons (Manger et al 2012) in different irradiation scenarios. In CT examinations, the absorbed dose was calculated for a simple eyeball modeled in a stylized phantom (Akhlaghi et al 2015c), for eye, cornea, and lenses in a stylized head phantom , and also for eye bulb and lens using voxel phantoms (Akhlaghi et al 2015b;Lee et al 2011).…”

Section: Discussionmentioning

confidence: 99%

“…Till now, these models have been widely used for calculation of dose conversion coefficients of the eye lens (Behrens et al 2009;Behrens and Dietze 2010;Nogueira et al 2011;Manger et al 2012;Sakhaee et al 2015;Vejdani-Noghreiyan and EbrahimiKhankook 2016). One of the most detailed models is the one designed by Nogueira and co-workers, in which lens cells were divided into sensitive and insensitive, and GZ was considered as the sensitive zone to ionizing radiation (Nogueira et al 2011).…”

Section: Introductionmentioning

confidence: 99%

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The effects of simulating a realistic eye model on the eye dose of an adult male undergoing head computed tomography

Akhlaghi

Ebrahimi-Khankook

Vejdani-Noghreiyan

2017

Radiat Environ Biophys

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In head computed tomography, radiation upon the eye lens (as an organ with high radiosensitivity) may cause lenticular opacity and cataracts. Therefore, quantitative dose assessment due to exposure of the eye lens and surrounding tissue is a matter of concern. For this purpose, an accurate eye model with realistic geometry and shape, in which different eye substructures are considered, is needed. To calculate the absorbed radiation dose of visual organs during head computed tomography scans, in this study, an existing sophisticated eye model was inserted at the related location in the head of the reference adult male phantom recommended by the International Commission on Radiological Protection (ICRP). Then absorbed doses and distributions of energy deposition in different parts of this eye model were calculated and compared with those based on a previous simple eye model. All calculations were done using the Monte Carlo code MCNP4C for tube voltages of 80, 100, 120 and 140 kVp. In spite of the similarity of total dose to the eye lens for both eye models, the dose delivered to the sensitive zone, which plays an important role in the induction of cataracts, was on average 3% higher for the sophisticated model as compared to the simple model. By increasing the tube voltage, differences between the total dose to the eye lens between the two phantoms decrease to 1%. Due to this level of agreement, use of the sophisticated eye model for patient dosimetry is not necessary. However, it still helps for an estimation of doses received by different eye substructures separately.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The effects of simulating a realistic eye model on the eye dose of an adult male undergoing head computed tomography

Akhlaghi

Ebrahimi-Khankook

Vejdani-Noghreiyan

2017

Radiat Environ Biophys

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“…Solid curves give the final values of ICRP reference conversion coefficients for external neutrons as a function of neutron energy. Manger et al (2012) concluded that the dose to the sensitive region of the lens of the eye was similar to that of the total lens over all neutron energies and exposure geometries, with the greatest differences being 13% at the lowest incident neutron energy. Regardless of the orientation of the exposure, no significant difference was found in the absorbed dose in the sensitive volume and total volume of the lens of the eye.…”

Section: Electron Irradiation Of the Eyementioning

confidence: 99%

“…Geometric eye model of Manger et al (2012) for neutron dosimetry In 2012, the previous studies of electron and photon eye dosimetry were further extended to neutron ocular exposures. In a study by Manger et al (2012), the stylised eye model of Behrens et al (2009) was again adopted and inserted into a larger model of the head and neck. In this study, the latter model selected was that of the modified Oak Ridge National Laboratory stylised phantom as reported by Han et al (2006).…”

Section: Geometric Eye Model Of Behrens and Dietze (2011) For Photon mentioning

confidence: 99%

Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures

Bolch

Dietze²,

Petoussi-Henss

et al. 2015

Ann ICRP

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Based upon recent epidemiological studies of ocular exposure, the Main Commission of the International Commission on Radiological Protection (ICRP) in ICRP Publication 118 states that the threshold dose for radiation-induced cataracts is now considered to be approximately 0.5 Gy for both acute and fractionated exposures. Consequently, a reduction was also recommended for the occupational annual equivalent dose to the lens of the eye from 150 mSv to 20 mSv, averaged over defined periods of 5 years. To support ocular dose assessment and optimisation, Committee 2 included Annex F within ICRP Publication 116 . Annex F provides dose coefficients - absorbed dose per particle fluence - for photon, electron, and neutron irradiation of the eye and lens of the eye using two dosimetric models. The first approach uses the reference adult male and female voxel phantoms of ICRP Publication 110. The second approach uses the stylised eye model of Behrens et al., which itself is based on ocular dimensional data given in Charles and Brown. This article will review the data and models of Annex F with particular emphasis on how these models treat tissue regions thought to be associated with stem cells at risk.

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“…In this study, a modified Oak Ridge National Laboratory (ORNL) adult phantom (Miri Hakimabad et al, 2012) that included revisions reported in 1996 (Eckerman et al, 1996) and a thyroid model provided by Ulanovsky (Ulanovsky and Eckerman, 1998) were used. This latter phantom is the revised version of the Medical Internal Radiation Dose (MIRD) phantoms that have been widely used Lee et al, 2007;Manger et al, 2011).…”

Section: Introductionmentioning

confidence: 99%