Dose to the urinary bladder from radionuclides in urine

Unnikrishnan, K.

doi:10.1088/0031-9155/19/3/004

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…An optimum micturition volume also exists which, combined with the optimum injection time, minimizes the radiation dose for each hydration scheme. As the dependence of the minimal dose value on the micturition volume is weak, especially for V1 x 2 schemes, it is suggested that under controlled hydration conditions there is no need for the patient to void frequently, as was previously proposed (Diffey and Hilson 1976;Unnikrishnan 1974), but to void at certain time intervals which may be determined by the applied hydration protocol. Anyway, man is able to void at any degree of bladder filling (Muellner 1960).…”

Section: Discussionmentioning

confidence: 93%

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

et al. 1992

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A spherical bladder dynamic model for the estimates of the radiation dose to the bladder walls from intravenously injected radionuclides was implemented to investigate in theory the effect of hydration on the reduction of the bladder dose in technetium-99m diethylene triamine penta-acetic acid (99mTc) DTPA renography. This model gives due consideration to the variation with time of the urine flow rate to the bladder, following a known fluid load. According to the model, the estimated dose depends on the renal function, the fluid load, the time elapsed from the fluid load to the i.v. DTPA injection, the micturition volume and the residual urine volume. Experimental data concerning the values of these parameters for normal individuals were obtained from the literature. Calculations cover the time period from i.v. injection up to the time of the ninth postinjection void. Results show that the patient's condition of hydration is critical for the radiation protection of the bladder. It is shown that optimum combinations of the values of the parameters involved in the calculations exist, which minimize the radiation dose. On the basis of these results, a general protocol is proposed, referring to the hydration conditions under which the renal dynamic study may be normally carried out, with a minimal absorbed dose to the bladder walls (less than 0.045 mGy/MBq).

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Section: Discussionmentioning

confidence: 93%

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

et al. 1992

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Radiation dose to the bladder wall and the gonads from direct radionuclide cystography in children

Dimitriou¹,

Fretzayas²,

Nicolaidou³

et al. 1987

Eur J Nucl Med

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A dynamic spherical bladder model, previously developed in our laboratory, was implemented to evaluate the absorbed dose to the bladder wall from 99mTc-pertechnetate and direct radionuclide cystography (DRC). This model takes into account the flow rate of normal saline into the bladder and the bladder volume as a function of the filling time. The DRC examinations of 36 children were analysed and calculations were carried out in order to estimate (a) the absorbed dose to the bladder during and following the DRC examination and (b) the gonadal dose. It is shown that the estimated dose to the bladder wall is much greater than that estimated by static models. It is also shown that the absorbed dose to the bladder due to the activity in the residual urine following the examination is even greater than the dose received during the DRC procedure. Our results indicate that in order to reduce the radiation burden, besides the so far proposed precautions, concerning the shortening of the DRC procedure, the patient should also be well hydrated and encouraged to void frequently after the examination.

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Absorbed dose to the bladder from⁹⁹Tc^mDTPA

Diffey¹,

Hilson²

1976

BJR

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Dose to the urinary bladder from radionuclides in urine

Cited by 4 publications

References 2 publications

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

Radiation dose to the bladder wall and the gonads from direct radionuclide cystography in children

Absorbed dose to the bladder from⁹⁹Tc^mDTPA

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Dose to the urinary bladder from radionuclides in urine

Cited by 4 publications

References 2 publications

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

Radiation dose to the bladder wall and the gonads from direct radionuclide cystography in children

Absorbed dose to the bladder from99TcmDTPA

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Absorbed dose to the bladder from⁹⁹Tc^mDTPA