Doses baixas de dobutamina e fluidos no pós-operatório de pacientes de alto risco: efeitos sobre a oxigenação tecidual, resposta inflamatória e morbidade

Arantes, Adriana; Júnior, Antônio Carlos Christiano; Abreu, Sônia Portela de; Moraes, Janaína Maria Miranda Ferreira de; Gandolfi, Joelma Villafanha; Leite, Lauriane Gomes; Lobo, Suzana Margareth

doi:10.1590/s0103-507x2007000100001

Cited by 4 publications

(3 citation statements)

References 14 publications

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“…Of these 185, 15 were initially classified as randomized clinical trials. (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) These 15 original articles were analyzed regarding concealment of allocation, and six articles (17,(19)(20)(21)(22)(23) (40%) ranked as A, other six articles (10,(13)(14)(15)(16)18) (40%) ranked as B, two articles (11,12) (13.3%) as C and one article (9) (6.7%) that was not a randomized clinical trial was ranked as D.…”

Section: Resultsmentioning

confidence: 99%

“…Results of the quality assessment disclosed that 7% (1/13) of the articles were of good quality (22) (Table 1). Score distribution on the quality scale was: zero for 8 (57.2%) original articles (10)(11)(12)(13)(14)(15)(16)18) 2 points for 5 (35.7%) (17,(19)(20)(21)23) and 4 points for one (7.1%) original article that presented good methodological quality. (22) The assessment of the secondary variables of all original articles showed that: 110 (59.5%) original articles described submitting the project to a Committee of Ethics in Research, 53 (28.6%) described use of informed consent, 19 (10.3%) described sample size calculation, 146 (78.9%) described the variables analyzed, 118 (63.8%) described inclusion criteria, 90 (48.6%) described exclusion criteria and in only 3 (1.6%) was there a description of the funding source.…”

Section: Resultsmentioning

confidence: 99%

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Avaliação da qualidade dos ensaios clínicos aleatórios em terapia intensiva

Gonçalves¹,

Barbosa²,

Barbosa³

et al. 2009

Rev. bras. ter. intensiva

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Objective: A randomized clinical trial is a prospective study that compares the effect and value of interventions in human beings, of one or more groups vs. a control group. The objective of this study was to evaluate the quality of published randomized clinical trials in Intensive care in Brazil. Methods: All randomized clinical trials in intensive care found by manual search in Revista Brasileira de Terapia Intensiva from January 2001 to March 2008 were assessed to evaluate their description by the quality scale. Descriptive statistics and a 95 % confidence interval were used for the primary outcome. Our primary outcome was the randomized clinical trial quality. Results: Our search found 185 original articles, of which 14 were randomized clinical trials. Only one original article (7.1%) showed good quality. There was no statistical significance between the collected data and the data shown in the hypothesis of this search. Conclusion: It can be concluded that in the sample of assessed articles 7% of the randomized clinical trials in intensive care published in a single intensive care journal in Brazil, present good methodological quality.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Avaliação da qualidade dos ensaios clínicos aleatórios em terapia intensiva

Gonçalves¹,

Barbosa²,

Barbosa³

et al. 2009

Rev. bras. ter. intensiva

View full text Add to dashboard Cite

show abstract

“…This method was also used in another recent trial (2) . Therefore, this study's population consists of a well-defined group with a high risk of death.…”

Section: Authors' Replymentioning

confidence: 99%