Dosimetric Comparison Of One Arc, Double Arc VMAT And IMRT Techniques in High Risk Prostate Cancer with Pelvic Nodal Radiation Therapy and High Doses

İnanç, Berrin; Inanc, Kubilay; Coşkun, Bilgehan; Uyanoglu, Ahmet; Kızılkaya, Orhan; Yücel, Birsen

doi:10.4172/2155-9619.1000370

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…Evolving techniques will therefore combine IMRT with some form of image-guided radiotherapy (IGRT), in which organ movement can be visualized and corrected for in real-time. IGRT involves the incorporation of imaging before and/or during treatment to enable more precise verification of treatment delivery and allow for adaptive strategies to improve the accuracy of treatment [6,13]. surgery, as well as the use of antiplatelet drugs, had a significant impact on the occurrence of acute toxicity grade ≥ 1 of the lower gastrointestinal tract [15,16].…”

Section: Volumetric Modulated Arc Therapymentioning

confidence: 99%

Modern radiotherapy in the treatment of localized prostate cancer

2021

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Prostate cancer (PC) is one of the most prevalent cancers in men and the second leading cause of cancerrelated deaths, after lung cancer. The incidence and mortality from PC worldwide are correlated with increasing age. The treatment of patients is multidisciplinary, with radiotherapy being an integral part, whether applied as an independent method or in combination with surgery or systemic therapy. The technological progress in the middle of the last century, opened up new possibilities in the planning and conducting radiotherapy started the new era of radiotherapy called modern radiotherapy. Today, highly conformal external beam techniques such as intensity-modulated radiotherapy (IMRT) and volume-modulated arc therapy (VMAT) are used as the gold standard in PC radiotherapy. They enable the precise definition of tumor volume based on modern diagnostic procedures, with maximum sparing of the surrounding organs. Advanced conformal techniques have also led to an escalation of the tumor dose, thus achieving better local control of the disease with significant reduction of early and late complications of treatment, the quality of life of PC patients is preserved. In addition to technological progress, modern radiotherapy includes monitoring the side effects of radiotherapy, and assessment of clinical and individual parameters that affect sensitivity and response to radiation. This should enable personalized radiotherapy with optimization of the treatment for each patient, which is one of the goals of modern oncology.

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Section: Volumetric Modulated Arc Therapymentioning

confidence: 99%

Modern radiotherapy in the treatment of localized prostate cancer

2021

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“…However, Double Arc VMAT plans generally result in increased MU, Beam on time and low dose spread compared to Single Arc VMAT plan. (Radhakrishnan et al, 2017;Inanc et al, 2018;Richter et al, 2019;Tol et al, 2015;Guckenberger et al, 2009;Chow et al, 2013;Vanetti et al, 2009;Verbakel et al, 2009). There are various approaches proposed to improve VMAT plan by introducing partial arc or full arc with avoidance sectors to avoid the portion of the arc which contributes relatively less.…”

Section: Introductionmentioning

confidence: 99%

A Novel Method for Improving VMAT Plan Quality and Deliverability

Ramar

Meher

2022

Asian Pac J Cancer Prev

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Background: A new VMAT method called "Augmented Arc" (or simply Aug Arc) is proposed. The aim of this study is to demonstrate the validity of the proposed method in different clinical cases. Basically, Aug Arc refers to the portion(s) of the VMAT arc that is augmented with an additional arc to improve the plan quality. The Aug Arc portions in the Arc is determined using an objective function-based scoring method called "ψ -score". Methods: To validate our approach, we have applied it in four clinical cases: Lung, Abdomen, Gynecologic (Gyn) and Pancreas. Basically, for Lung and Pancreas cases, four sets of plans were created, which are: (1) Single arc plan (S Arc), (2) Double arc plan (D Arc), (3) Partial Arc plan without Aug Arc (P Arc) and (4) Partial plan with Aug Arc (P+Aug Arc). For Abdomen and Gyn cases, three sets of plans were created, which are: (1) Single arc plan (S Arc), (2) Double arc plan (D Arc) and(3) Single Arc with Aug Arc (S+Aug Arc). To compute the "ψ -score", an initial optimization was performed by using full Arc with 4-degree gantry spacing. Subsequently, Aug Arc portions were identified using the ψ -score plot in the single arc and partial arc scenarios. Results: The study finds that the proposed method is useful to improve the plan quality and plan deliverability for both centrically and non-centrically located tumors in terms of reducing the OAR dose, monitor units, beam on time and low dose volume without compromising the target coverage. Conclusion: The results indicate that the proposed approach could strike a balance between full double arc and single arc or partial arc in such a way that the planner can find a sweet spot of delivery parameters that result in optimal plan quality.

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Dosimetric Comparison Of One Arc, Double Arc VMAT And IMRT Techniques in High Risk Prostate Cancer with Pelvic Nodal Radiation Therapy and High Doses

Cited by 2 publications

References 21 publications

Modern radiotherapy in the treatment of localized prostate cancer

Modern radiotherapy in the treatment of localized prostate cancer

A Novel Method for Improving VMAT Plan Quality and Deliverability

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