Dosimetry assessment of patient-specific 3D printable materials for HDR surface brachytherapy

Bassi, Sarah; Langan, Brian; Malone, Ciaran

doi:10.1016/j.ejmp.2019.10.035

Cited by 17 publications

(14 citation statements)

References 14 publications

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“…Bassi et al used EBT3-V3 lm for dosimetry assessment of a 3D printable material in surface BT as a mold. Their results were in good agreement with Oncentra ® Brachy TPS when two lms were irradiated at 5 mm and 15 mm distance from their 3D-printed 5 mm slab [27]. However, there is no report for dosimetry data in the distance less than 5 mm near the BT source due to the high dose gradient.…”

Section: Discussionsupporting

confidence: 57%

“…As it is shown in Figure 6, loss of scattering equilibrium or any positional uncertainty leads to a difference up to 35% between calculated dose in lm and TPS at the surface of the phantom. Several studies used EBT2 or EBT3 lms as a dosimeter in various BT dosimetry procedures [27][28][29][30]. Sinnantamby et al performed a veri cation study to evaluate the radiation dosimetry in HDR-BT by EBT2 lm.…”

Section: Discussionmentioning

confidence: 99%

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Validation of an Individualized Home-Made Superficial Brachytherapy Mould Applied for Non-Melanoma Skin Cancer

Jaberi¹,

Siavashpour²,

akha³

et al. 2021

Preprint

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Purpose: This study was conducted to evaluate the effect of a Brachytherapy (BT) customized mold (Condensation silicone elastomer (Protesil TM )) thickness ,on dose distribution pattern in deeper lesions used for nonmelanoma skin cancers (NMSC).Material and Method: MOSFET TM and GAFCHROMIC TM EBT3 film dosimeters were used for the different thicknesses of a Brachytherapy (BT) customized mold (up to 20 mm), skin dose and dose in different depths were evaluated.Result: The received dose to the surface is overestimated by TPS.Skin dose can be reduced from 250 to 150% of prescription dose by increasing mold thickness from 5 mm to 20 mm. There was a 7.7% difference in calculated dose by TPS and measured dose by MOSFET. Film dosimetry data was unreliable. There was a good agreement between film dosimetry, MOSFET detector, and TPS results, in the depth of 5mm<.Conclusion: Any individualized material chosen to use for making the customized surface BT mold should be validated at BT departments. Protesil TM can be selected as feasible material to make any form of superficial molds. For thicker NMSC lesions up to 20 mm using thicker molds up to 20 mm can be. Even for 10 mm lesions, by changing mold thickness from 5 mm to 20 mm, skin dose would reduce. Protesil TM can be used to make an individualized superficial BT mold. By increasing the mold thickness, lesions can be treated without overexposing the skin surface and skin dose reduced by increasing mold thickness. So, superficial BT can be recommended as an appropriate treatment option for NMSC lesions with some consideration.

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Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Validation of an Individualized Home-Made Superficial Brachytherapy Mould Applied for Non-Melanoma Skin Cancer

Jaberi¹,

Siavashpour²,

akha³

et al. 2021

Preprint

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“…After including additional abbreviated keywords, 28 publications were found for AM in superficial skin BT, which formed the basis of this review. These included 8 clinical case studies [30][31][32][33][34][35][36][37], 7 physical and dosimetric evaluations [38][39][40][41][42][43][44], 6 proof-of-concept cases [45][46][47][48][49][50], 6 design process assessments [51][52][53][54][55][56], and 1 economic feasibility study [57]. All these articles, except for one, were published since 2015.…”

Section: Current Literature Profile Of Additive Manufacturing In Superficial Brachytherapymentioning

confidence: 99%

“…Water-equivalency and treatment planning dose comparisons can be checked using radiochromic film measurements. Several studies have reported on the dosimetric properties of various AM materials, specifically the dose fall-off over appropriate distances and through different material thicknesses [38][39][40][41][42][43][44]. In each study, the authors declared the tested material water-equivalent, possessing comparable properties to a water-equivalent material, or measured dose through the material equivalent to those predicted by the treatment planning system (TPS).…”

Section: Assessing Dosimetric Quality Of Materialsmentioning

confidence: 99%

“…In fitting with the appropriateness of using superficial BT to treat irregular topologies, noses are the most prevalent types treated with AM applicators according to various clinical research publications. One author noted that reproduc-ibility of setup was actually better with an irregular topology and an AM applicator due to inherent indexing of the applicator on the anatomy and less risk of mispositioning compared to a flat surface [38]. Lecornu et al identified that to facilitate placement on facial sites, constructs that would enable elastics loops for around the ears or head are useful in applicator's design [33].…”

Section: Treatment and Case Studiesmentioning

confidence: 99%

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Additive manufacturing (3D printing) in superficial brachytherapy

Bellis¹,

Rembielak²,

Barnes³

et al. 2021

jcb

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The aim of this work is to provide an overview of the current state of additive manufacturing (AM), commonly known as 3D printing, within superficial brachytherapy (BT). Several comprehensive database searches were performed to find publications linked to AM in superficial BT. Twenty-eight core publications were found, which can be grouped under general categories of clinical cases, physical and dosimetric evaluations, proof-of-concept cases, design process assessments, and economic feasibility studies. Each study demonstrated a success regarding AM implementation and collectively, they provided benefits over traditional applicator fabrication techniques. Publications of AM in superficial BT have increased significantly in the last 5 years. This is likely due to associated efficiency and consistency benefits; though, more evidences are needed to determine the true extent of these benefits.

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Characterization of novel 3D‐printed metal shielding for brachytherapy applicators

McGrath,

Chytyk‐Praznik,

Cherpak

2024

J Applied Clin Med Phys

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PurposeTo characterize 3D‐printed stainless steel metal samples in the presence of an Iridium‐192 source for organ‐at‐risk sparing in gynecologic brachytherapy.MethodsSamples of 3D‐printed stainless steel (5.5 × 5.5 cm2, thickness range 1–5 mm) were embedded in a solid water phantom at varying distances from source catheters. An Ir‐192 brachytherapy source was passed through the phantom and the dose was measured using EBT3 Gafchromic film. The film was initially positioned in the sagittal plane 2 cm away from the catheters, with the metal directly below and then 1 cm from the film. A uniform dose was delivered at the film plane. A second setup measured a depth dose curve in solid water with film in the transverse plane directly above the metal samples. This setup was recreated using Monte Carlo simulations (EGSnrc egs_brachy). Validation between methods was performed with unshielded (solid water only) measurements.ResultsThe planar dose passing through the metal samples (thickness 1–5 mm) at the midpoint between the film and catheters, decreased compared to solid water by 7.4% ± 6.9% to 26.5% ± 5.5%. Dose enhancement on the order of 5% was noted when metal was directly adjacent to the film. The average decrease in depth dose from a single dwell position ranged from 10.0% ± 5.9% (1 mm) to 21.1% ± 5.3% (5 mm) as measured with film, and from 3.8% ± 0.9% (1 mm) to 16.3% ± 0.9% (5 mm) using MC simulation. The average depth dose values were measured using a line width of 2.5 mm for film, and 3 mm for MC simulation, and the measurements generally agree within standard error.ConclusionsThe 3D‐printed metal samples show potential for personalized applicators. Maximum dose reduction of 26.5% ± 5.5% compared to solid water was measured at 2 cm from the source using the 5 mm sample. An outer layer of solid water could potentially be used to reduce dose enhancement due to increased scatter near the metal.

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Dosimetry assessment of patient-specific 3D printable materials for HDR surface brachytherapy

Cited by 17 publications

References 14 publications

Validation of an Individualized Home-Made Superficial Brachytherapy Mould Applied for Non-Melanoma Skin Cancer

Validation of an Individualized Home-Made Superficial Brachytherapy Mould Applied for Non-Melanoma Skin Cancer

Additive manufacturing (3D printing) in superficial brachytherapy

Characterization of novel 3D‐printed metal shielding for brachytherapy applicators

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