Double Glomus Tumors Originating in the Submandibular and Parotid Regions

Yoo, Young Joon; Choi, Jeong Hwan; Heo, Gyunyoung; Kim, Sang Woo; Kim, Hyun Jung

doi:10.3342/ceo.2011.4.1.49

Cited by 3 publications

(5 citation statements)

References 13 publications

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“…Glomus tumors are rare, accounting for fewer than 2% of soft tissue tumors. However, nearly 10% of cases involve multiple lesions [3]. This tumor is most common in the skin or superficial soft tissue, particularly in the subungual region, and can be found in deep soft tissue and internal organs (such as the nerves, bone, penis, bladder, mediastinum, gastrointestinal tract, liver, and cervix) [4,5].…”

Section: Discussionmentioning

confidence: 99%

“…(3) Glomangiomyoma: this type is the rarest, with an overall structure similar to that of a solid tumor or hemangioma, but with a transition between typical cells and spindle cells resembling mature smooth muscle. Glomus tumors may occur in deep-seated, visceral locations throughout the body, including the lung, pancreas, liver, and gastrointestinal and genitourinary tract [3]. Here, we report the clinicopathologic and immunohistochemical features of gastric glomus tumors (GGTs) seen in two institutions, with the aim of achieving a better understanding of this rare tumor and providing a reference for clinical treatment.…”

Section: Introductionmentioning

confidence: 99%

“…Immunohistochemical assays for CgA, Syn, and panCK are positive, and SMA and vimentin negativity can be identified [11]. [3] Paraganglioma: paraganglioma in the stomach is rare. The tumor cells are composed of chief cells and sustentacular cells, which are arranged in nests and found in organs around the blood vessels.…”

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confidence: 99%

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Gastric Glomus Tumor: A Clinicopathologic and Immunohistochemical Study of 21 Cases

Lin

Shen

Hao

et al. 2020

BioMed Research International

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Gastric glomus tumors (GGTs) are rare mesenchymal tumors. Most glomus tumors occur in the distal parts of the extremities. Here, we retrospectively analyzed the features of GGTs from two institutions. The histologic and clinical findings of all GGT cases from 2009 to 2018 were reviewed. The most common location was the antrum, the mean age of patients was 49.3 years, and the mean tumor size was 2.1 cm. Microscopically, small, round cell nodules surrounded the expansion of blood vessels in a nest pattern. Immunohistochemical assays for vimentin and smooth muscle actin (SMA) were positive, and assays for H-caldesmon and calponin were partially positive. GGT is rare and easily misdiagnosed before operation. However, immunohistochemistry is useful for the differential diagnosis. The majority of GGTs are benign, and local surgery achieving complete resection is the most effective treatment method.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Gastric Glomus Tumor: A Clinicopathologic and Immunohistochemical Study of 21 Cases

Lin

Shen

Hao

et al. 2020

BioMed Research International

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“…7 The etiology of the glomus tumors remains unclear; however, familial glomus tumors found to have an autosomal dominant pattern with incomplete penetration. 13 Yoo et al 14 reported a case of double glomus tumors in the submandibular and parotid regions. Sixty percent of patients with multiple glomus tumors have had a positive family history, supporting the concept that this abnormality is an inherited disease.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Glomus Tumor on the Mucosal Surface of Lower Lip

Rad

Najirad

Rafiei

2020

Journal of Investigative Medicine High Impact Case Reports

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Glomus tumors are mesenchymal neoplasms derived from glomus bodies with rare presentations in the oral cavity. Glomus tumors present as a purple or pink vascular nodule or papule, sized <1 cm, and imitate vascular neoplasms such as hemangiopericytoma or hemangioma. Glomus tumors represent less than 2% of all benign soft tissue tumors. Only 27 cases of benign glomus tumors with oral cavity involvement have been reported to date. The most-reported oral tumors involved the lips (54.2%), followed by hard palate, gingiva, tongue, and buccal mucosa. The mean age of presentation of the labial glomus tumors is 48.7 years, with no gender predilection, in contrast to the subungual site, which occurs more in females. The etiology of the glomus tumors remains unknown. Subungual glomus tumors present as stabbing pain, cold intolerance, and tenderness of the fingertips, whereas labial glomus tumors mostly present as a painless, small, and slow-growing lesion. Treatment is surgical resection of the tumor. The recurrence rate of labial glomus tumors is unclear. In this article, we present the case of a 62-year-old man with a 2-month history of painless, soft lump on the mucosal surface of the lower left lip. Excisional resection of the tumor was performed in the clinic, and the histopathologic finding was consistent with solid glomus tumor. At 1 year follow-up there was no recurrence.

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“…Multiple glomus tumor is a rare benign neoplasm that arises from the glomus body in the stratum reticularis of the dermis, the highly specialized arteriovenous anastomosis for thermoregulation. 1 , 2 , 3 , 4 Although several cases of multiple glomus tumor involving the anterior thigh, 5 submandibular and parotid regions, 6 the torso, 7 have been reported, radiological characteristics on MRI images for multiple glomus tumor have not been described. We reported here both pre-operative and post-operative MR images from a case of 16 years old girl with multiple glomus tumor that partially coalesced on the anterior side of the leg.…”

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confidence: 99%