Estimates of knee joint loadings were calculated for 12 normal subjects from kinematic and kinetic measures obtained during both level and downhill walking. The maximum tibiofemoral compressive force reached an average load of 3.9 times body-weight (BW) for level walking and 8 times BW for downhill walking, in each instance during the early stance phase. Muscle forces contributed 80% of the maximum bone-on-bone force during downhill walking and 70% during level walking whereas the ground reaction forces contributed only 20% and 30% respectively.Most total knee designs provide a tibiofemoral contact area of 100 to 300 mm 2 . The yield point of these polyethylene inlays will therefore be exceeded with each step during downhill walking. Several recent studies have reported severe wear of polyethylene tibial components. 1-4 The long-term problems associated with joint wear debris, such as loosening and infection, are well known. Wear is dependent on a number of factors including contact area, load, material properties, thickness of the polyethylene inlay and the length of time that the component has been implanted. 1,5 The most destructive wear process is fatigue, which occurs through repeated high loads and cyclic stressing. Load is dependent both on physical activity and on body-weight. The increasing long-term successes being achieved with total knee replacement means that younger, and consequently more active, patients are being treated. This places an increased mechanical demand on the prosthesis which exceeds the design limits of many of the currently used devices.The moments and forces about the knee vary substantially for different daily activities.6 Biomechanical studies of knee joint loading have consistently estimated maximum joint compressive forces to be about 4 to 4.5 times bodyweight during daily activities. 7 This range of values has become a design criterion for most currently used knee prostheses, but recent studies have indicated that loadings can be much higher even during level walking. 9,10 This finding is consistent with the increasing incidence of reports of severe wear in joint replacements. 1,2,4,[11][12][13][14] We present quantitative joint load data and suggest new criteria for use in the biomechanical evaluation of total knee prostheses.
MATERIALS AND METHODSWe obtained estimates of knee joint loading for 12 normal subjects (6 male and 6 female) ranging in age from 23 to 37 years (mean 27.9), in height from 158 to 187 cm (mean 171) and in weight from 49 to 90 kg (mean 70.8). Reflective markers were located superficial to the 5th metatarsophalangeal, ankle, knee and hip joints. Spatial trajectories were recorded using a video-based motion analysis system with two cameras sampling at 60 Hz (APAS, Ariel Dynamics, Inc, Trabuco Canyon, California) whilst the subjects walked across a level floor and down a purpose-built ramp of 19% gradient. Ground reaction force data were simultaneously obtained from a Kistler force platform (Type 9281B, Winterhur, Switzerland). Ground reaction forces during...