Draft genome of the medicinal tea tree Melaleuca alternifolia

Zhang, Xiaoning; Chen, Silin; Zhang, Ye; Xiao, Yufei; Qin, Yufeng; Li, Qing; Liu, Li; Liu, Buming; Chai, Linjiang; Yang, Hong; Liu, Hailong

doi:10.1007/s11033-022-08157-8

Cited by 8 publications

(4 citation statements)

References 29 publications

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“…), EOs are known as tea tree oil (TTO). This TTO is used in the pharmaceutical, cosmetic, and food industries due to its antimicrobial, antioxidant, anti-inflammatory, and antineoplastic properties [ 30 , 31 , 32 ]. Adulteration of TTO happens, which may be related to confusion with the common name (tea tree) of some species in the genus Leptospermum , and species in the genera Kunzea and Baeckea from Australia and New Zealand, which also have the same common name.…”

Section: Components Of Tea Tree Oil (Tto) and Their Variabilitymentioning

confidence: 99%

“…Adulteration of TTO happens, which may be related to confusion with the common name (tea tree) of some species in the genus Leptospermum , and species in the genera Kunzea and Baeckea from Australia and New Zealand, which also have the same common name. Nevertheless, the financial gain can be the most important factor in the adulteration of TTO [ 31 ], through the addition of lower-cost byproducts derived from Eucalyptus essential oil or even through the addition of pure chemical compounds obtained by chemical synthesis or fermentation [ 33 ].…”

Section: Components Of Tea Tree Oil (Tto) and Their Variabilitymentioning

confidence: 99%

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Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

et al. 2023

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Acne vulgaris is an inflammatory dermatological pathology that affects mostly young people. However, it can also appear in adulthood, mainly in women. It has a high psychosocial impact, not only at the time of active lesions but also due to the consequences of lesions such as scarring and hyperpigmentation. Several factors are involved in the physiopathology of acne and the constant search for active ingredients is a reality, namely phytotherapeutic ingredients. Tea tree oil is an essential oil extracted from Melaleuca alternifolia (Maiden & Betch) Cheel with known antibacterial, anti-inflammatory, and antioxidant properties, making it a candidate for the treatment of acne. This review aims to describe the various properties of tea tree oil that make it a possible ingredient to use in the treatment of acne and to present several human studies that have evaluated the efficacy and safety of using tea tree oil in the treatment of acne. It can be concluded that tea tree oil has good antibacterial, anti-inflammatory, and antioxidant properties that result in a decrease in the number of inflammatory lesions, mainly papules, and pustules. However, given the diversity of study designs, it is not possible to draw concrete conclusions on the efficacy and safety of this oil in the treatment of acne.

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Section: Components Of Tea Tree Oil (Tto) and Their Variabilitymentioning

confidence: 99%

Section: Components Of Tea Tree Oil (Tto) and Their Variabilitymentioning

confidence: 99%

Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

et al. 2023

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“…A combination of bioinformatics tools was used to identify MYB gene family in M. alternifolia. Arabidopsis MYB protein sequences (available at http://www.phytozome.net/phytochrome) were utilized as query sequences in the M. alternifolia genomic [13][14] and transcriptome data (CNCB, PRJCA019034). 252 candidate MYB proteins were obtained and con rmed for the presence of the MYB domain using NCBI Conserved Domain Search2 [15] and SMART program3 [16].…”

Section: Identi Cation and Classi Cation Analysismentioning

confidence: 99%

“…However, the function of the MaMYB gene family needed to be fully explored. With the release of its genomic information [13][14], we conducted a comprehensive investigation of the MYB gene family in Melaleuca alternifolia. The results include the characterization of the phylogenetic relationship, gene structures, conserved motifs, and functional annotation of 219 MaMYB genes, as well as the evaluation of their expression patterns in different ages of M. alternifolia.…”

Section: Introductionmentioning

confidence: 99%

Identification of MYB Gene Family in medicinal tea tree Melaleuca alternifolia (Maiden & Betche) Cheel and Analysis of Members Regulating Terpene Biosynthesis

Zhang,

Xu,

Liu

et al. 2023

Preprint

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Background The tea tree (Melaleuca alternifolia) is renowned for its production of tea tree oil (TTO), an essential oil primarily composed of terpenes extracted from its shoot. MYB transcription factors, which are one of the largest TF families, play a crucial role in regulating primary and secondary metabolite synthesis. However, knowledge of the MYB gene family in M. alternifolia is limited. Methods and results Here, we conducted a comprehensive genome-wide analysis of MYB genes in M. alternifolia, referred to as MaMYBs, including phylogenetic relationships, structures, promoter regions, and GO annotations. Our findings classified 219 MaMYBs into four subfamilies: one 5R-MYB, four 3R-MYBs, sixty-one MYB-related, and the remaining 153 are all 2R-MYBs. Seven genes (MYB189, MYB146, MYB44, MYB29, MYB175, MYB162, and MYB160) were linked to terpenoid synthesis based on GO annotation. Phylogenetic analysis with Arabidopsis homologous MYB genes suggested that MYB193 and MYB163 may also be involved in terpenoid synthesis. Additionally, through correlation analysis of gene expression and metabolite content, we identified 42 MYB genes associated with metabolite content. Conclusion The results provide valuable insights into the importance of MYB transcription factors in essential oil production in M. alternifolia. These findings lay the groundwork for a better understanding of the MYB regulatory network and the development of novel strategies to enhance essential oil synthesis in M. alternifolia.

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Identification of MYB gene family in medicinal tea tree Melaleuca alternifolia (Maiden and Betche) cheel and analysis of members regulating terpene biosynthesis

Zhang,

Xu,

Liu

et al. 2024

Mol Biol Rep

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Draft genome of the medicinal tea tree Melaleuca alternifolia

Cited by 8 publications

References 29 publications

Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

Identification of MYB Gene Family in medicinal tea tree Melaleuca alternifolia (Maiden & Betche) Cheel and Analysis of Members Regulating Terpene Biosynthesis

Identification of MYB gene family in medicinal tea tree Melaleuca alternifolia (Maiden and Betche) cheel and analysis of members regulating terpene biosynthesis

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Draft genome of the medicinal tea tree Melaleuca alternifolia

Cited by 8 publications

References 29 publications

Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

Identification of MYB Gene Family in medicinal tea tree Melaleuca alternifolia (Maiden &amp; Betche) Cheel and Analysis of Members Regulating Terpene Biosynthesis

Identification of MYB gene family in medicinal tea tree Melaleuca alternifolia (Maiden and Betche) cheel and analysis of members regulating terpene biosynthesis

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Identification of MYB Gene Family in medicinal tea tree Melaleuca alternifolia (Maiden & Betche) Cheel and Analysis of Members Regulating Terpene Biosynthesis