Dressings and topical agents for surgical wounds healing by secondary intention

Vermeulen, Hester; Ubbink, Dirk T.; Goossens, Astrid; Vos, Rien de; Legemate, Dink A.; Westerbos, S. J.

doi:10.1002/14651858.cd003554.pub2

Cited by 99 publications

(60 citation statements)

References 42 publications

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“…28 Epigrof group cost effectiveness has not been evaluated by any clinical trial as stated by R Eldor et al 29 Most of the patients in the mentioned literature Virginia AC et al, Vermeulen H and Xakellis GC have been treated as out-patients hence could not be directly correlated with present study. 1,2,5 Pain and sensitivity observation in the present study corelates to the study by P Halankar who found hypertrophic scarring in 2 patients treated with collagen sheet. 10 Scar status had similar findings as was seen in study by Tuyet HL where only 1 female patient had overgranulation.…”

supporting

confidence: 90%

Effect of moist dressing, collagen sheet dressing and epidermal growth factor in healing of chronic wounds

Jain¹,

Tote²,

Kolte³

et al. 2017

Int Surg J

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Background: Surgical literature is full of innumerable solutions to the problems of wound healing and it speaks of itself that the problem is not so simple and straight forward to tackle with. The aim of the present study was to compare three modalities moist saline dressing, collagen sheet dressing and epidermal growth factor in early epithelization and healing of chronic wounds. to study the effect of various dressing modalities on epithelization of chronic wound in terms of time required for healing and the quality of scar it forms, the functional results both early and late, post-healing morbidity and complications and the practicality and the cost involved in using these modalities.Methods: Prospective randomized controlled study. Study including chronic wound cases admit to AVBRH Sawangi over period of 3 years.Results: Reduction in size of wound by 70-100% was found highest in Epigrof group. In Epigrof treated group 88% of wounds healed within 3 weeks while 80% in collagen group and 56% in moist dressing group it. Collagen dressing is the most cost effective of the three whereas Epigrof was most costly due to the initial cost of purchase. The scar quality was satisfactory in 19 of Epigrof group and 17 of the collagen sheet group and 15 of the moist dressing group.Conclusions: Epidermal growth factor is superior in epithelization, collagen is the next best local applicant, but collagen sheet is more cost effective than Epigrof and non-adherent dressings.

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supporting

confidence: 90%

Effect of moist dressing, collagen sheet dressing and epidermal growth factor in healing of chronic wounds

Jain¹,

Tote²,

Kolte³

et al. 2017

Int Surg J

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“…7 Sharp Debridement had average cost of Rs 2180/-the cost effectiveness of this group correlates with study by Young T. 13 Moist dressing group patients were treated on OPD basis as in the mentioned literature Virginia AC et al, Vermeulen H and Xakellis G C have been treated as out-patients. 9,12,14 Hospitalization was required in debridement group hence the costing of hospital stay increased by overall cost of treatment decreased due to early return back to life. As was mentioned in study by Hoppe I.…”

Section: Discussionmentioning

confidence: 99%

Role of early debridement in non-healing ulcer

Tote¹,

Jajoo²,

Tote³

2017

Int Surg J

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Background: Non-healing wound is a commonly encountered entity with a broader effect on both the sufferer and the treating doctor. Time taken in healing these wound is directly related to financial loss as well as loss of working hours, thus ultimately increasing the financial burden. Chronic wound has devitalized tissue at the base which is barrier to cell migration and acts as supportive environment for bacterial growth. Considering the effect of devitalized tissue on wound healing there lies importance of debridement in wound management. Debridement is an effective technique to achieve desirable wound bed preparation by removing the dead and devitalized tissue. Hence a study was conducted at a rural hospital with main aim to assess role of surgical sharp debridement in non-healing wound in complete healing or preparing wound for further definitive treatment.Methods: The study was conducted at AVBRH Sawangi (Meghe), Wardha. Random 50 patients of non-healing ulcer were selected for the study. One group was of early debridement while other group of dressing with moist dressing only. Wound were assessed for healing, wound contraction, scar quality at regular intervals. They were assessed for duration of wound to heal completely/ get ready for further intervention like SSG/ Flaps, Cost of treatment and Time taken by the patient to return back to work.Results: 36% of patients in moist dressing group heal completely by 4 weeks while 56% of patients in debridement group heal completely by 4 weeks. Early recovery leads to early normalcy so less loss of wages and thus making the group cost effective.Conclusions: Early debridement was found to be an effective tool in wound healing in non-healing ulcers.

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“…When used on the surface of the body that involves frequent bandage deformation (e.g., limbs, elbow joints), an important aspect of choosing material is studying its bursting properties when wet [12][13][14][15]. Depending on the type and structure of material, the bursting stress value varies significantly.…”

Section: Khokhlenkova Et Almentioning

confidence: 99%

Development of Methodical Approaches to the Creation of the Pharmacologically Active Bandage

Хохленкова

et al. 2017

Asian J Pharm Clin Res

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The results of modern research on the creation of pharmacologically active bandage were generalized. The main components of the development of pharmacologically active dressing (choice of active ingredients, carrier substrate, the method of immobilization, etc.) were determined. Methodological approaches to the creation of pharmacologically active bandage were developed. The practical significance of the developed methodological approaches was demonstrated by research and development of dressings with thick oak bark extract.

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Dressings and topical agents for surgical wounds healing by secondary intention

Cited by 99 publications

References 42 publications

Effect of moist dressing, collagen sheet dressing and epidermal growth factor in healing of chronic wounds

Effect of moist dressing, collagen sheet dressing and epidermal growth factor in healing of chronic wounds

Role of early debridement in non-healing ulcer

Development of Methodical Approaches to the Creation of the Pharmacologically Active Bandage

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