Driving sleepiness is still a major causes of traffic accidents. Individual drivers, under various conditions, act and respond in different manners. This article presents the attempt of a straight-line driving simulator study that examined the effects of driver behavior style differences and individual differences on driver sleepiness detection which is based on driving performance measures. A total of 15 drivers who were classified into two categories through subjective assessment based on a Driver Behavior Questionnaire participated in driving simulator experiments. A total of 18 detection models, including 15 SE models for each subject, an A model for the aggressive drivers, an NA model for the non-aggressive drivers, and a G model for all experiment participants, were developed using support vector machine method based on driving performance characteristic parameters. The results show that the G model is not suitable for all drivers due to its lower mean accuracy of 69.88% (standard deviation = 7.70%) and higher standard deviation. The SE models for each subject show the best detection accuracy performance of 84.26% (standard deviation = 5.38%); however, it is impossible to set up a special detection model for every individual driver. The SD models on different style categories show an accuracy value of 77.54% (standard deviation = 5.78%). The results demonstrate that driver style differences as well as individual differences have great effects on driver sleepiness detection (F = 19.148, p \ 0.000).