Change and innovation are increasingly exerting a significant influence on the daily activities of companies. To ensure optimal control, innovative solutions are employed that are encapsulated in the concept of change management. In the engineering change sector, the proposed approach involves developing solutions and making continuous adjustments to the manufacturing process to enhance productivity and to meet customer needs. Within the automotive industry, companies utilize innovations and process change management to continuously improve and strengthen their position in the market, such as KPI/KPRS and PCI. To achieve this, the present study gathers real digital data from the Romanian branches of two renowned automotive companies. The data regarding change requests include 215 registrations for the first company and 734 registrations for the second company. By employing complex statistical methods such as ANOVA, Student’s t-test, the Mann–Whitney test, and a regression model, the primary objective of this study is to model and to identify the best predictor of change request status. Additionally, this study aims to explore how this change process influences the economic performances of the companies and the performance indicators of change management in manufacturing processes. The findings indicate that, both in the organizations in general and within the automotive industry, when products experience high demand in the market, the number of change requests increases. This highlights the importance of internal optimization of the automation system. Moreover, the study results underscore the crucial role of an effective smart manufacturing and optimal change management system to uphold and to enhance the economic performance of automotive companies.