Drop coating deposition Raman (DCDR) spectroscopy of contaminants

Detection and Characterization of Nodularin by Using Label-Free Surface-Enhanced Spectroscopic Techniques

“…As demonstrated in previous studies [ 70 , 71 , 72 ], DCDR analysis showed detection sensitivity superior to conventional Raman for small biological molecules, such as acetylsalicylic acid, riboflavin, and contaminants [ 73 , 74 ], down to a detection limit of 10 −8 M. It also proved to be an important tool for membrane-interaction studies, such as the liposome–porphyrin complex [ 75 ], for the quantitative determination of creatinine in urine [ 76 ], and for colorectal cancer detection in blood plasma [ 77 ]. The advantages of DCDR analysis include the use of dried, preconcentrated samples, a small sample volume, no interference from solvents, and the capability to segregate any existing impurities [ 76 ].…”

Drop coating deposition Raman (DCDR) spectroscopy of biologically important molecules

“…Moreover, normal Raman spectra from stock solutions of these substances were impossible to obtain under the same experimental conditions. The lowest DCDR detected concentrations were determined as 6.4, 0.31, 20 and 2 mM in deposited concentrations for melamine, thiram, bentazon and picloram, respectively 37 …”

“…The observed patterns can be composed of small crystals and/or non‐uniform spots that are more or less homogenous. Small molecules include a broad set of substances, such as amino acids, porphyrins, dipicolinic acid, acetylsalicylic acid, riboflavin, methylene blue, contaminants (food and environmental) and so forth 33–37 . We reported the improvement of detection sensitivity for cationic (copper(II) 5,10,15,20‐tetrakis(1‐methyl‐4‐pyridyl)porphyrin) and anionic (copper(II) 5,10,15,20‐tetrakis(4‐sulfonatophenyl) porphyrin) porphyrins by a factor of 10 5 when the DCDR spectra from ~20 nM deposited concentrations were acquired.…”

“…Small molecules include a broad set of substances, such as amino acids, porphyrins, dipicolinic acid, acetylsalicylic acid, riboflavin, methylene blue, contaminants (food and environmental) and so forth. [33][34][35][36][37] We reported the improvement of detection sensitivity for cationic (copper (II) 5,10,15,20-tetrakis(1-methyl-4-pyridyl)porphyrin) and anionic (copper(II) 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin) porphyrins by a factor of 10 5 when the DCDR spectra from $20 nM deposited concentrations were acquired. Moreover, we measured the DCDR spectrum of protoporphyrin IX known as a marker in clinical diagnostics of cancer, even from 10 nM deposited concentration.…”

Identification and classification of particle contaminants on photomasks based on individual-particle Raman scattering spectra and SEM images

“…[19][20][21] Raman shi corresponds to the vibration or rotation mode of the corresponding chemical bond, which can realize the detection and identication of the small particle. [22][23][24][25] It is therefore of great advantage in the analysis of the structure of compounds. E. M. Malykhin et al investigated the structure and chemical properties of carbon lms under 13.5 nm UV irradiation using Raman and IR spectroscopy, respectively.…”