Drug-based magnetic imprinted nanoparticles: Enhanced lysozyme amyloid fibrils cleansing and anti-amyloid fibrils toxicity

Lasting Tracking and Rapid Discrimination of Live Gram-Positive Bacteria by Peptidoglycan-Targeting Carbon Quantum Dots

“…In vivo and in vitro experiments were performed to verify the biological safety of the three typical CQDs. We first explored its cytotoxicity by CCK-8 assay in NRK cells. , As shown in Figure S21, the NRK cells treated with the different concentrations of CQDs exhibited greater than 80% viability after incubation for 24 h. Next, the three types of CQDs were extensively analyzed by H&E staining for histological assessment of tissue interactions and inflammation. The major organs including hearts, livers, spleens, lungs, kidneys, and skin were collected from mice after PBS (control) or CQD treatment and stained with H&E. , The bioimaging system revealed that the three types of CQDs caused no damage to normal organs and skin (Figure S22).…”

A novel aggregation-induced emission poly(phosphoramidate): fluorescence properties and visual detection for Cu2+

“…S11) after removing Cu 2+ by ethylenediaminetetraacetic acid disodium salt (EDTA-2Na). Furthermore, we expolre the biocompatibility of PPA by CCK-8 assays 36 , and the results are shown in Fig. S12, we can see that the cell viability more than 84% after incubation for 24 h with the concentration of PPA as high as 1.0 mg mL -1 , indicating the excellent biocompatibility of PPA.…”

Dual-targeted carbon-dot-drugs nanoassemblies for modulating Alzheimer's related amyloid-β aggregation and inhibiting fungal infection

“…Currently, most of A β inhibitors including biomolecules [ [23] , [24] , [25] , [26] ], functionalized nanomaterials and nanoparticles [ 16 , 17 , [27] , [28] , [29] , [30] , [31] ], have been shown to decelerate the aggregation of A β and suppress cellular toxicity of amyloid. For example, Sun et al.…”