Drug‐eluting stenting of unprotected left main coronary artery stenosis in patients with orthotopic heart transplantation: Initial clinical experience

Abstract

In OHT patients, ULMCA PCI with DES is feasible with an excellent technical success rate and is a reasonably palliative treatment option for this difficult patient population.

Comparison of Percutaneous Coronary Intervention With Bare-Metal and Drug-Eluting Stents for Cardiac Allograft Vasculopathy

“…Coronary artery bypass surgery is rarely performed, because CAV is associated with poor distal targets attributable to the diffuse nature of the disease and greater perioperative mortality (7)(8)(9)(10)(11)(12). Percutaneous coronary intervention (PCI) has been used as a palliative treatment option for CAV but has been associated with greater procedural and long-term morbidity and mortality and higher restenosis rates compared with native coronary artery lesions (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25).…”

Treatment of Left Main Coronary Artery Stenosis with Drug-Eluting Stent Following Heart Transplantation

“…In a follow-up study on five patients who received drug-eluting stents for left main disease, all survived after a follow up of 518 days (range 124-990 days) with no major adverse cardiac events (18). In a multicenter retrospective analysis on 21 patients with allograft vasculopathy involving the left main coronary artery, angiographic success was achieved in 100% of patients.…”

Long-term clinical outcomes after percutaneous coronary intervention for unprotected left main coronary artery in heart transplant patients with cardiac allograft vasculopathy

“…The reference lists of these reports were also reviewed. Of these 12 manuscripts (mostly case reports and case series), two reports [27,28] were excluded as they reported outcomes on the same patients at different follow-up periods. The 10 remaining reports [17][18][19][20][21][22][23][24][25][26] were thoroughly reviewed, and data on baseline clinical and socio-demographic characteristics, coronary anatomy and stent type (drug eluting vs. bare metal) were extracted.…”

“…Initial search resulted in 347 citations. The titles and abstracts of these citations were reviewed for patients with CAV and a total of 12 reports were selected for detailed review [17][18][19][20][21][22][23][24][25][26][27][28]. The reference lists of these reports were also reviewed.…”