Drug-induced diseases in otolaryngology – causes, clinical signs, treatment

Woroń, Jarosław; Jurkiewicz, Dariusz; Rapiejko, Piotr; Lorkowska-Zawicka, Barbara; Tymiński, Radosław; Wordliczek, Jerzy

doi:10.5604/01.3001.0014.7445

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…A total of 16 records were included in this macro-category. Some of these (n = 7) include a case of hyperprolactinemia/galactorrhea [135], three cases of moderate-to-severe allergic skin reactions with petechial and pruritic features [136,137], a case of ingravescent acneiform eruption [138], a case of tinnitus [139], a case of acutely arising hemoptysis [140], and a case of restless leg syndrome [141]. There was also a report relating to a case of Call-Fleming syndrome or Reversible Cerebral Vasoconstriction Syndrome (RCVS), which arose in a twenty-year-old woman seven weeks after vortioxetine introduction.…”

Section: Descriptive Observational Studiesmentioning

confidence: 99%

The Role of Vortioxetine in the Treatment of Depressive Symptoms in General Hospital Psychiatry: A Case-Series and PRISMA-Compliant Systematic Review of the Literature

Weiss,

Pacciardi,

D’Alessandro

et al. 2024

JCM

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Depressive symptoms are a customary finding in hospitalized patients, particularly those who are undergoing long hospitalizations, underwent major surgical procedures or suffer from high levels of multimorbidity and frailty. The patients included in this case series shared high degrees of frailty-complexity and were evaluated within the ordinary consultation and liaison psychiatry service of the University Hospital in Pisa, Italy, from September 2021 to June 2023. Patients were administered at least one follow-up evaluation after a week and before discharge. To relate this case series to the extant literature, a comprehensive systematic review of vortioxetine safety and efficacy was performed. None of the six patients included developed serious safety issues, but one patient complained of mild-to-moderate nausea for some days after the vortioxetine introduction. Five out of six patients exhibited at least a slight clinical benefit as measured by the clinical global impression scale. Of the 858 entries screened via Scopus and Medline/PubMed, a total of 134 papers were included in our review. The present case series provides preliminary evidence for vortioxetine’s safety in this healthcare domain. The literature reviewed in this paper seems to endorse a promising safety profile and a very peculiar efficacy niche for vortioxetine in consultation and liaison psychiatry.

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Section: Descriptive Observational Studiesmentioning

confidence: 99%

The Role of Vortioxetine in the Treatment of Depressive Symptoms in General Hospital Psychiatry: A Case-Series and PRISMA-Compliant Systematic Review of the Literature

Weiss,

Pacciardi,

D’Alessandro

et al. 2024

JCM

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show abstract

Multiple drugs interaction

2021

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Multiple drugs interactionHearing loss, dizziness and tinnitus: 30 case reports A study described 30 patients (9 men and 21 women) aged 51-89 years, who developed hearing loss, dizziness or tinnitus following the concomitant administration of various improper combinations of drugs [dosages, routes and durations of treatments to reactions onsets not stated].Out of the 30 patients, 11 patients developed dizziness following concomitant administration of diclofenac, omeprazole and ginkgo biloba (1 patient), naproxen, omeprazole and propafenone (1 patient), mirtazapine, ticlopidine and amiodarone (1 patient), doxepin, celecoxib and omeprazole (1 patient), sertraline, memantine and omeprazole (1 patient), amlodipine, buprenorphine and ginkgo biloba (1 patient), atorvastatin, amiodarone and terbinafine (1 patient), atorvastatin, trazodone and silybum-marianum [milk thistle] (1 patient), simvastatin, haloperidol and ginkgo biloba (1 patient), atorvastatin, ivabradine and diltiazem (1 patient), doxepin, ticlopidine and metoprolol (1 patient), 17 patients developed tinnitus following concomitant administration of etoricoxib, ginkgo biloba and atorvastatin (1 patient), tramadol, ginkgo biloba and diphenhydramine (1 patient), tramadol, metoprolol and diphenhydramine (1 patient), tramadol, quetiapine and propafenone (1 patient), sertraline, ginkgo biloba and omeprazole (1 patient), duloxetine, omeprazole and propafenone (1 patient), amlodipine, ginkgo biloba and trazodone (1 patient), amlodipine, inkgo biloba and terbinafine (1 patient), irbesartan, omeprazole and lorazepam (1 patient), vortioxetine, amiodarone and propafenone (1 patient), doxazosin and amiodarone (1 patient), doxazosin, atorvastatin and diphenhydramine (1 patient), escitalopram, ginkgo biloba, omeprazole and quetiapine (1 patient), acemetacin, ginkgo biloba and omeprazole (1 patient), diclofenac, ginkgo biloba and omeprazole (1 patient), diclofenac, omeprazole and buprenorphine (1 patient), sertraline, omeprazole and clopidogrel (1 patient), and the remaining two patients developed hearing loss following concomitant administration of clarithromycin, carvedilol and atorvastatin (1 patient) or clarithromycin [Klarytromycyna], tamoxifen [tamoksifen] and atorvastatin [atorwastatyna](1 patient).After modification of the combination of drugs, the symptoms improved in 25 patients and resolved in 2 patients [not all outcomes stated].

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Drug-induced diseases in otolaryngology – causes, clinical signs, treatment

Cited by 2 publications

References 4 publications

The Role of Vortioxetine in the Treatment of Depressive Symptoms in General Hospital Psychiatry: A Case-Series and PRISMA-Compliant Systematic Review of the Literature

The Role of Vortioxetine in the Treatment of Depressive Symptoms in General Hospital Psychiatry: A Case-Series and PRISMA-Compliant Systematic Review of the Literature

Multiple drugs interaction

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