2010
DOI: 10.1111/j.1754-4505.2009.00126.x
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Drug‐induced gingival enlargement: Biofilm control and surgical therapy with gallium–aluminum–arsenide (GaAlAs) diode laser—A 2‐year follow‐up

Abstract: Drug-induced gingival enlargement has been reported in patients treated with various types of anticonvulsant drugs, and is generally associated with the presence of plaque, gingival inflammation, and a genetic predisposition. Effective treatment includes daily oral hygiene and periodic professional prophylaxis. However, in some patients, surgical removal of the gingival tissue overgrowth becomes necessary. The patient in this case report was mentally impaired and had severe drug-induced gingival enlargement. T… Show more

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Cited by 20 publications
(11 citation statements)
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“…11 Nonsurgical periodontal treatment (including oral hygiene instruction, scaling, root planing, and prophylaxis) is the conventional management approach for gingival enlargement but is not always effective when gingival enlargement is extensive and self-care is compromised. 12 This in turn has led to surgical approaches to the management of gingival enlargement. However, this is considered by many as very invasive and may not be effective if self-care oral hygiene practices remain poor.…”
Section: Introductionmentioning
confidence: 99%
“…11 Nonsurgical periodontal treatment (including oral hygiene instruction, scaling, root planing, and prophylaxis) is the conventional management approach for gingival enlargement but is not always effective when gingival enlargement is extensive and self-care is compromised. 12 This in turn has led to surgical approaches to the management of gingival enlargement. However, this is considered by many as very invasive and may not be effective if self-care oral hygiene practices remain poor.…”
Section: Introductionmentioning
confidence: 99%
“…Reported cases of gingival enlargements were induced by different drugs; CCBs (50/119 – of which amlodipine-25;[8910111213141516171819202122232425262728] nifedipine-13;[26293031323334353637383940] verapamil-4;[41] felodipine-2;[4243] nisoldipine-1;[44] manidipine-1;[45] and unspecified CCBs-4[46]); phenytoin (11/119);[4748495051525354555657] cyclosporine (31/119);[3546585960616263646566676869707172737475] phenobarbital (4/119);[767778] sodium valproate (3/119 - including one report of congenital drug-induced gingival hyperplasia);[798081] d-penicillamine (2/119);[82] combination oral contraceptive pill-lynestrenol and ethinyl estradiol (1/119);[83] vigabatrin (1/119). [84] Cases of gingival enlargement after combination drug therapy have also been reported; a combination of cyclosporine and CCBs (11/119);[354685...…”
Section: Resultsmentioning
confidence: 99%
“…The use of mouth rinses is a useful adjunctive self-care approach to the management of gingival enlargement, but it, too, relies on patient compliance; in addition, there can be some side effects with long-term use (29). Nonsurgical periodontal treatment (including oral hygiene instruction, scaling, root planing, and prophylaxis) is the conventional management approach for gingival enlargement but is not always effective when gingival enlargement is extensive and self-care is compromised (30).…”
Section: Adjunct Procedures For Periodontal Therapymentioning
confidence: 99%