Drug-induced ophthalmic adverse reactions

Cox, Anthony R.; Gilmartin, Bernard

doi:10.1097/01.fad.0000295368.90978.4f

Cited by 3 publications

(5 citation statements)

References 27 publications

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“…20,[81][82][83] Ipratropium bromide, an anticholineric agent used to relive bronchoconstriction causes mydriasis and might precipitate an ACAG attack in susceptible individuals. 3,[84][85][86] Three of five patients who developed ACAG after receiving ipratropium and salbutamol experienced bilateral ocular involvement. 84 Tiotropium bromide, another anticholinergic agent, has weaker anticholinergic activity, but has been reported to induce ACAG.…”

Section: Respiratory System Agentsmentioning

confidence: 99%

Non-steroidal drug-induced glaucoma

Razeghinejad

Pro

Katz

2011

Eye

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Numerous systemically used drugs are involved in drug-induced glaucoma. Most reported cases of non-steroidal drug-induced glaucoma are closed-angle glaucoma (CAG). Indeed, many routinely used drugs that have sympathomimetic or parasympatholytic properties can cause pupillary block CAG in individuals with narrow iridocorneal angle. The resulting acute glaucoma occurs much more commonly unilaterally and only rarely bilaterally. CAG secondary to sulfa drugs is a bilateral non-pupillary block type and is due to forward movement of iris-lens diaphragm, which occurs in individuals with narrow or open iridocorneal angle. A few agents, including antineoplastics, may induce open-angle glaucoma. In conclusion, the majority of cases with glaucoma secondary to non-steroidal medications are of the pupillary block closed-angle type and preventable if the at-risk patients are recognized and treated prophylactically.

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Section: Respiratory System Agentsmentioning

confidence: 99%

Non-steroidal drug-induced glaucoma

Razeghinejad

Pro

Katz

2011

Eye

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“…Thus, the practicing eye care professional plays an important role in identifying and reporting the potential ocular side‐effects induced by commercially available medicines (Santodomingo‐Rubido et al. , 2003; Cox and Gilmartin, 2006; Gilmartin, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Although some countries have voluntary post-marketing surveillance systems, they can suffer from under-reporting, incomplete case report information and lack of case follow-up. Thus, the practicing eye care professional plays an important role in identifying and reporting the potential ocular side-effects induced by commercially available medicines (Santodomingo-Rubido et al, 2003;Cox and Gilmartin, 2006;Gilmartin, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…The role of the UK optometrist in detecting and reporting ocular adverse reactions to systemic medication was established over 30 years ago (Gilmartin, 1987, 2008) and has developed substantially in recent years (Edgar and Gilmartin, 1997; Lawrenson, 2001; Cox and Gilmartin, 2006). Although the professional optometric literature regularly reviews drug‐induced adverse ocular side‐effects of interest to the practicing optometrist (e.g.…”

Section: Introductionmentioning

confidence: 99%

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Drug‐induced ocular side‐effects with isotretinoin

Santodomingo-Rubido¹,

Barrado-Navascués²,

Rubido-Crespo³

2008

Ophthalmic Physiologic Optic

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Whereas there are numerous reported ocular side-effects from isotretinoin medication, we present the first case report of corneal steepening after systemic treatment with isotretinoin for seven and a half weeks. The case was associated with a significant drop in visual acuity which could not be explained from the refractive error change. All signs and symptoms were absent seven and a half weeks after the medication was withdrawn. The case indicates that eye care professionals need to be vigilant about the possibility of adverse ocular manifestations associated with the use of systemic medications.

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“…A stable tear film is essential for normal vision, ocular comfort and maintenance of a healthy ocular surface environment . The meibomian glands secrete the lipid layer of the tears, and are essential to reduce tear evaporation and maintain tear film stability.…”

mentioning

confidence: 99%