Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Associated with Ampicillin-Sulbactam and Clindamycin: A Case Report

Özdemir, Öner; Genç, Gökçe

doi:10.4274/imj.galenos.2018.89421

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…Taking into consideration the chest X-ray, the authors also initiated antibiotic treatment with clindamycin, which can be used even in severe cases of penicillin anaphylactic shock (13). The most difficult aspect of this case was the progression towards acute respiratory distress through acute epiglottis edema.…”

Section: Discussionmentioning

confidence: 99%

Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report

et al. 2020

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A case is presented of a male with drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by carbamazepine intake. The patient presented all the elements of DRESS syndrome: Skin reaction, fever, enlargement of the lymph nodes, increased eosinophils and lymphocytes, with associated organ dysfunctions. The patient was admitted with acute laryngeal edema and imminence of respiratory insufficiency. The escalation of symptoms for this syndrome is typical, even after the administering of the the culprit medicine has ceased. However, in this case, the most difficult aspect was the complex treatment scheme prior to admission. All medical compounds involved in the background treatment were substituted with other substances in order to control the immune response. Current knowledge regarding DRESS is reviewed and possible influence of various etiologies over the present case are discussed. Clinicians should be aware of this rare situation with life-threatening potential. We benefited from the advantage of reuniting the knowledge of a complex team of experts from various tertiary emergency units in Romania.

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Section: Discussionmentioning

confidence: 99%

Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report

et al. 2020

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DRESS Syndrome After Lamotrigine Use in A Epilepsy Patient: A Case Report

Engin¹,

Kaya²,

Arsoy³

et al. 2021

Sakarya Medical Journal

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CASE REPORT / Olgu SunumuÖz DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) sendromu ilaca bağlı akut bir aşırı duyarlılık reaksiyonudur. DRESS sendromu; ateş, deri döküntüsü, lenfadenopati, hematolojik anormallikler (eozinofili, atipik lenfositler), iç organ (karaciğer veya diğer) tutulumu ile karakterize olarak morbidite ve mortaliteye neden olabilir. DRESS sendromuna en sık neden olan ilaçlar antikonvülzanlar, dapson, sülfonamidler, allopurinol ve minosiklindir. Klinik bulgular genellikle sorumlu ilacın başlamasından 1-7 hafta sonra gelişir, bu süre üç aya kadar uzayabilir. Ölüm oranının % 10'lara kadar ulaştığını ve en önemli ölüm nedeninin karaciğer yetmezliği olduğunu bildiren makaleler vardır. DRESS sendromu için tanı kriterleri RegiSCAR grubu tarafından oluşturulmuştur. Bu yazıda lamotrijin tedavisi sonrası DRESS sendromu gelişen bir çocuk olgusu sunularak güncel tanı ve tedavi yaklaşımları ile ilgili literatür gözden geçirilmiştir.

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Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Associated with Ampicillin-Sulbactam and Clindamycin: A Case Report

Cited by 2 publications

References 18 publications

Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report

Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report

DRESS Syndrome After Lamotrigine Use in A Epilepsy Patient: A Case Report

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