Drug utilization of oral hypoglycemic agents in a university teaching hospital in India

Abstract

This study strongly highlights the need for patient education or counselling on use of antidiabetic and concomitant drugs, monitoring of blood glucose and glycosylated haemoglobin (HbA1c) levels, diet control, and correction of diabetic complications. Metabolic control was poor and HbA1c monitoring was underutilized. Clinical monitoring of patients' adherence to prescribed treatments is recommended and measures should be taken to improve it.

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“…Average number of drugs per prescription was 4.2 in present study that were much higher as compared to other studies in India, reporting an average of 2.27 drugs per prescription 16 . In this present study a combination of two antidiabetics were mostly (40.625%) prescribed.…”

“…The age (mean ± SD) of the patients experiencing adverse effects due to antidiabetics was 43.2 ± 9.55 years which was much lower, compared to other studies in India (51.5 ± 12.3 years) 16,17 , Hongkong (56.5 ± 12.6 years) 18 and West Indies (58.9 ± 3.4 years) 19 . Present study highlighted that 40.63% of these adverse drug events were reported in patients of age group of 36-45 years.…”

A Drug Utilisation Study of Antihyperglycaemic Agents in a Rural Tertiary Care Hospital

“…Average number of anti-Diabetic drugs 1.8 which is less than study done by Sultana G etal, 2010. [8] The percentage of diabetics receiving insulin during the hospital stay was higher than the study done by Sultana G etal, 2010 [8] but less than Abdi SH etal, 2012. [6] The combination of metformin with glimipiride was most commonly used dual therapy according to the present study which was comparable to other studies.…”

Drug utilization study on antidiabetic medications at SIMS-Shimoga a tertiary care hospital

“…This was more than the average number antidiabetic prescribed in Adbi et al 9 where the average number of drugs was 0.94. It was, however, <2.27 recorded in a study conducted by Sultana et al 10 2010. The increase in the number of drugs may be due to increased number of co-morbidities in the patient population as well as the use of combination therapy even amongst antidiabetic agents.…”