This study strongly highlights the need for patient education or counselling on use of antidiabetic and concomitant drugs, monitoring of blood glucose and glycosylated haemoglobin (HbA1c) levels, diet control, and correction of diabetic complications. Metabolic control was poor and HbA1c monitoring was underutilized. Clinical monitoring of patients' adherence to prescribed treatments is recommended and measures should be taken to improve it.
Rapidly rising antibiotic resistance is a challenge to comprehensive patient care in all branches of medical science. A retrospective observational study was conducted to determine the antimicrobial resistance patterns in a tertiary care hospital for six months. The data was collected from laboratory test reports and patient case files using a structured data collection form. A total of 200 cases having a positive culture report were included in the study. Of these, 186 cases were identified to have gram-negative infections, and 14 had gram-positive infections. Escherichia coli (E. Coli) (47%) was the predominant isolate among gram-negative organisms, followed by Klebsiella (24.5%), Pseudomonas (7.55%), Enterobacter (6.5%), and Citrobacter (4.5%). All Gram-positive organisms E.coli, Klebsiella, Pseudomonas, Enterobacter have shown maximum resistance of 92.55%, 95.91%, 93.33%, and 76.92%, respectively, Ampicillin. E.coli has shown the least resistance to carbapenems (7.44%). Klebsiella demonstrated minimum reistance of 10.2% to cefotaxime, cefazolin and levofloxacin. Pseudomonas was completely sensitive to piperacillin-tazobactam. Enterobacter showed least resistance to gentamicin (3.07%) and piperacillin-tazobactam (3.07%). The primary gram-positive isolate, Enterococcus spp. (5.5%) mainly was resistant to ciprofloxacin (90.90%), followed by levofloxacin (81.81%), tetracycline (81.81%), and gentamicin (72.72%). E. coli was the most resistant organism in the present study. The study results would contribute to the development of an antibiogram at the study site.
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