Drug utilization pattern in geriatric inpatients of medicine department in a Tertiary Care Teaching Hospital

Nayaka, Swapna R; Bv, Rajeshwari; Venkatadri, T V

doi:10.18203/2319-2003.ijbcp20150042

Cited by 11 publications

(17 citation statements)

References 5 publications

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“…The majority of the patients (41%) belonged to the age group of 65-70 years, and least were in the age group of 86-90 years (9%), which is similar to previous studies on geriatric patients conducted in India [16]. However, in a similar study conducted in South India showed more female population [22].…”

Section: Discussionsupporting

confidence: 88%

“…Similar studies conducted at Karnataka [22] showed it to be 70% whereas in a study on geriatric population conducted in Pondicherry [16] found it to be 21.31%, which is much less than ours.…”

Section: Discussioncontrasting

confidence: 70%

“…This may be due to psychological advantage of injections on patients and treating doctors. Whereas, in a similar study conducted in India [22], it was 26.33%, and is within acceptable limits.…”

Section: Discussionmentioning

confidence: 55%

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A Study of Drug Utilization Pattern of the Geriatric Patients in the Department of Geriatric Medicine in a Tertiary Care Hospital in Assam, India

Borah

Devi

Debnath

et al. 2017

Asian J Pharm Clin Res

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Objective: To investigate the drug utilization pattern and the prevalence of potentially inappropriate medications (PIMs) using updated AGS Beers Criteria 2012 among the elderly patients who attended the geriatric outpatient departments as well as admitted indoor patients in a Tertiary Care Hospital at Guwahati, Assam, India. Methods:A hospital-based prospective, observational and cross sectional study, involving patients aged 65 years and above was planned and conducted over a period of 6-months from January 2016 to June 2016. Patients were visited daily, interviewed and case records were collected. Data were analyzed using Microsoft Office Excel Sheets.Results: A total of 150 patients aged 65 years and above were analyzed. 97 patients (65%) were males and 53 (35%) were females. Majority of the patients (61 numbers, 41%) belonged to the age group of 65-70 years, and least were in the age group of 86-90 years (13 numbers, 9%). Prescription of five or more medications (polypharmacy) was observed in 117 (78%) patients. Majority of the patients presented with diseases of cardiovascular system (25.7%). Using the World Health Organization drug use indicators, the average number of drugs per prescription was found to be 5.6. The percentage of drugs prescribed by generic name was 86%. The percentage of encounters in which antibiotics were prescribed was 61%. Injection was prescribed was 65% cases and the percentage of drugs prescribed from the National List of Essential Medicines of India was 96%. 43 patients received PIMs from Beers list; majority were belonging to Category 1. Spironolactone was most commonly prescribed PIM. Conclusion:Irrational prescribing practices and polypharmacy were detected in our study. Prescribers should be educated about the rational use of drugs and Beers Criteria for elderly.

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Section: Discussionsupporting

confidence: 88%

Section: Discussioncontrasting

confidence: 70%

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A Study of Drug Utilization Pattern of the Geriatric Patients in the Department of Geriatric Medicine in a Tertiary Care Hospital in Assam, India

Borah

Devi

Debnath

et al. 2017

Asian J Pharm Clin Res

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“…16 Pattern of age distribution contributed to the mean age of 69 years in the current study, similar to that (72.6 years) reported by by Jhaveri et al in a study conducted at Bhavnagar to evaluate the drug utilization pattern and pharmacoeconomics in geriatric medical inpatients. 17 Majority (80.9%) of patients suffered from more than one ailment which increases the risk of development of ADRs, similar to the findings of Nayaka et al in a study conducted to evaluate drug utilization pattern in geriatric medical inpatients at Bengaluru, India 18 and Shah et al in a study conducted to evaluate drug utilization pattern in geriatric patients in Gujarat, India. 19 A loss of functional reserve in the elderly renders them prone to development of multiple disorders, the commonest manifestation in the current study being cardiovascular disorders (67.1%).…”

Section: Discussionsupporting

confidence: 72%

An Intensive Monitoring of Adverse Drug Reactions among Elderly Patients Hospitalized in Medical Wards of a Tertiary Care Hospital

Kamejaliya¹,

Kapadia²,

Desai³

et al. 2017

JYP

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Objective: To evaluate the pattern of adverse drug reactions in elderly patients hospitalized in medical wards at a tertiary care hospital in India. Methods: Elderly patients ≥ 60 years hospitalized in three randomly selected medical units were enrolled and followed up daily till discharge. Detailed information of patients and ADRs were recorded by interviewing patients, doctors and nurses. Appropriateness of drug treatment in patients≥65 years was analyzed using Beer's criteria. ADRs were assessed for incidence, onset, duration, management, outcome, causality, severity, preventability, seriousness and risk factors. Results: A total of 1017 patients were enrolled (mean age: 69.5±7.6 years); majority (80.9%) suffered from >1 ailments. Patients received 6.3±0.5 drugs, commonly by oral (48%) and intravenous (41.6%) routes. Inappropriate drug therapy was observed in 76 patients of ≥65 years. ADRs were observed in 107(10.7%) patients, majority occurred within first week, commonly affected GI (29.9%), central and peripheral nervous system (17.8%) and were frequently associated with antimicrobials (44.2%), drugs acting on CVS (13.3%) and endocrine systems (12.5%). Majority of reactions were mild (55.1%), non-serious (73.8%), not preventable (85.9%), recovered completely at discharge (87.8%) and had possible causal association with suspect drug (68.2%). Age>80 years, ≥3 diseases, prescription of >10 drugs and hospitalization for>4 days were risk factors for occurrence of ADRs. Conclusion:Adverse reactios are common in elderly and were frequently affect gastrointestinal, central and peripheral nervous systems. Reactions are mild, non-serious and commonly caused by antimicrobials and drugs acting on cardiovascular or endocrine systems. Multiple diseases, polytherapy, age>80 years and hospitalization>4 days increase the risk of ADRs.

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“…16 The average age in our study was 67.34±6.91 years, whereas study by Nayaka et.al., the average age was 72.68 years. 17 A 34.55% of patients were illiterate 38.79% belonged to category of lower middle and 9.7% to upper socioeconomic classes compared to study by Nayaka et al, where 93% of patients were illiterate, 68% belonged to category of lower and 12% to higher socioeconomic classes.…”

Section: Demographicsmentioning

confidence: 75%

Drug usage pattern of anti-hypertensive drugs in elderly diabetic, hypertensive in-patients with or without impaired renal function in a tertiary care hospital

Bhandary

Bhandari

2018

Int J Basic Clin Pharmacol

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Background: Hypertension (HTN) and Diabetes mellitus (DM) are the leading contributors to the cardiovascular mortality and morbidity. Drug utilisation studies (DUS) are potential tools in the evaluation in health care systems. Objectives was to analyse the drug usage pattern of anti-hypertensives in elderly hypertensive diabetic in-patients in a tertiary hospital. To analyse drug usage pattern of anti-hypertensives in elderly hypertensive, diabetic in-patients with renal impairment in a tertiary hospital.Methods: The study population consisted of 165 hypertensive diabetic in-patients at Shri Dharmasthala Manjunatheshwara (SDM) Hospital. Questionnaire based study was conducted and prescriptions of patient with HTN and DM at and above the age of 60 years irrespective of gender were included.Results: Our study revealed that angiotensin receptor blockers (ARBs) were the most commonly prescribed (42.4%) class of anti-hypertensive drugs. In patients with impaired renal function also ARBs were the most common class prescribed (22.0%). Out of 35 anti-hypertensive fixed drug combinations (FDCs) prescribed the most frequent combination was combination with an ARBs (85.7%). There was a significant increase in the number of anti-hypertensive drugs prescribed in patients with impaired renal function when compared to patients without impaired renal function (p <0.05). The cost index was high, and the percentage cost variation was more than 100% in most of the anti-hypertensive drugs prescribed.Conclusions: This study shows that the most commonly prescribed anti-hypertensive drug class was ARBs in patients with and in patients without impaired renal function.

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Drug utilization pattern in geriatric inpatients of medicine department in a Tertiary Care Teaching Hospital

Cited by 11 publications

References 5 publications

A Study of Drug Utilization Pattern of the Geriatric Patients in the Department of Geriatric Medicine in a Tertiary Care Hospital in Assam, India

A Study of Drug Utilization Pattern of the Geriatric Patients in the Department of Geriatric Medicine in a Tertiary Care Hospital in Assam, India

An Intensive Monitoring of Adverse Drug Reactions among Elderly Patients Hospitalized in Medical Wards of a Tertiary Care Hospital

Drug usage pattern of anti-hypertensive drugs in elderly diabetic, hypertensive in-patients with or without impaired renal function in a tertiary care hospital

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