Drug utilization study in genitourinary infections used as a teaching tool for rational therapy for MBBS students in a Medical College at Dehradun, Uttarakhand

Dutta, Shakti B.; Beg, Mirza Atif; Bawa, Shalu; Kaur, Amanjot

doi:10.5455/2319-2003.ijbcp20150407

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…In the current study it was seen that UTIs were almost equally distributed in both genders whereas in some other studies a higher incidence was seen in women, while yet other studies reported more incidence in men. [11][12][13][14][15] The highest incidence was seen in the age group of 18-30 years, which is similar to that was reported, while other studies reported more incidence in a higher age group. 3,11,16 The commonest causative organism was found to be Escherichia coli which is in concordance with other reports.…”

Section: Discussionsupporting

confidence: 77%

Drug utilization pattern and physician adherence to treatment guidelines in inpatients with urinary tract infection

Sharma

Oommen

2018

Int J Basic Clin Pharmacol

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Background: Mainstay of management in urinary tract infection (UTI) is antibiotics and it is seen in recent years that antibiotic resistance is increasing. However, very few treatment guidelines exist for UTI and often treating physicians may not adhere to these guidelines. Aims: Current study was undertaken to analyze antimicrobial prescription pattern and utilization, and check for physician adherence to treatment guidelines in UTI.Methods: This retrospective, record-based study was carried out in a tertiary care hospital in inpatients with UTI. Tabulated data was analyzed using WHO core drug prescribing indicators and Anatomical Therapeutic Chemical/ Defined Daily Dose (ATC/DDD) index. Adherence to treatment guidelines was assessed using Indian Standard Treatment Guidelines for Urology. Data documented in SPSS software was analyzed using χ2-test and multinomial logistic regression.Results: Among 364 patients included in study, equal incidence of UTI was seen in both sexes (male to female ratio 1.02:1). Prolonged hospital stay (>7 days) was associated with elderly age group (OR=3.09, CI95% 1.83-5.21), complicated UTI (OR=8.11, CI95% 4.62-14.24), ESBL-producing E. coli (OR=3.07, CI95% 1.58-5.94), non-adherence to treatment guidelines (OR=8.65, CI95% 4.19-17.84), and presence of comorbid conditions like diabetes mellitus (OR=4.89, CI95% 3.05-7.82), benign prostatic hypertrophy (OR=2.76, CI95% 1.36-5.59) and utero-vaginal prolapse (OR=8.33, CI95% 2.28-30.45). Average number of drugs prescribed per encounter was 1.59, while drugs prescribed by generic name and from essential drug list were 98.1% and 70.69% respectively. Majority of prescriptions (87.6%) adhered to standard treatment guidelines. Prescribed daily dose (PDD) and defined daily dose (DDD) were equal for most antibiotics prescribed.Conclusions: Majority of prescriptions were adhering to treatment guidelines but the need to prescribe using generic name and from essential drug list should be emphasised upon.

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Section: Discussionsupporting

confidence: 77%

Drug utilization pattern and physician adherence to treatment guidelines in inpatients with urinary tract infection

Sharma

Oommen

2018

Int J Basic Clin Pharmacol

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“…A study reported findings with almost 90% drugs were prescribed by their respective brand name. 37 However a recent retrospective, record-based study recorded a contradictory finding with 98.1% drugs prescribed in generic form in a tertiary care hospital in inpatients with urinary tract infection. 38 Prescribing by generic name needs to be promoted in our hospital to curb drug duplication, medication error and adverse effects due to medication therapy.…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Use Evaluation in Genitourinary Tract Infections in Female Patients at a Tertiary Care Hospital

Alam¹,

Sharma²,

Dubey³

et al. 2020

jemds

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A B S T R A C T BACKGROUNDGenitourinary tract infections are some of the most common infections in females. These problems are a challenge in terms of diagnosis and treatment. The present study was conducted to evaluate the prescribing pattern in three of the most common types of female genitourinary tract infections. METHODSA prospective and observational study was conducted on genitourinary tract infections in female patients at the gynaecology outpatient department in a tertiary care university hospital. RESULTSMajority of the infected female patients were in 26 -35 years age group (31.8%) followed by 36 -45 years age group (25.9%). The common infection noticed was urinary tract infection (42.2%), followed by pelvic inflammatory disease (32.2%) and vaginitis (25.5%) in infected female patients. The types of antibiotics prescribed for urinary tract infection were aminoglycosides, fluoroquinolones, cephalosporins and penicillins. The commonly prescribed antibiotics for pelvic inflammatory disease were tetracyclines, azoles, fluoroquinolones and cephalosporins, and for vaginitis azoles and aminoglycosides. The most commonly prescribed class of antibiotics for urinary tract infection, pelvic inflammatory disease and vaginitis were fluoroquinolones (11.8%), azoles (11.8%) and aminoglycosides (15.7%), respectively. Oral route was the preferred mode of administration (71%), followed by rectal (suppositories, 17.2%) and topical (cream, 11.8%). CONCLUSIONSYoung married women in this urban Indian community have a high prevalence of genitourinary tract infections but seldom seek treatment. Education and outreach are needed to reduce the stigma, embarrassment and lack of knowledge related to genitourinary tract infections.

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“…The WHO drug use indicators are highly standardized and are recommended for inclusion in drug utilization studies. 8 Antimicrobial resistance is one of the major global preventable problems. The causes of antimicrobial resistance are unnecessary use, inappropriate doses, inadequate duration of therapy and irrational fixed dose drug combinations.…”

Section: Discussionmentioning

confidence: 99%

Study of antimicrobial prescribing pattern in a tertiary care teaching hospital at Dehradun, Uttarakhand, India - A tool to teach clinical pharmacology to MBBS students

Beg

Bawa

Dutta

et al. 2016

Int J Basic Clin Pharmacol

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Drug utilization study in genitourinary infections used as a teaching tool for rational therapy for MBBS students in a Medical College at Dehradun, Uttarakhand

Cited by 3 publications

References 6 publications

Drug utilization pattern and physician adherence to treatment guidelines in inpatients with urinary tract infection

Drug utilization pattern and physician adherence to treatment guidelines in inpatients with urinary tract infection

Antibiotic Use Evaluation in Genitourinary Tract Infections in Female Patients at a Tertiary Care Hospital

Study of antimicrobial prescribing pattern in a tertiary care teaching hospital at Dehradun, Uttarakhand, India - A tool to teach clinical pharmacology to MBBS students

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