“Dry” NiCo2O4 nanorods for electrochemical non-enzymatic glucose sensing

Abstract

A rod-like NiCo 2 O 4 modified glassy carbon electrode was fabricated and used for nonenzymatic glucose sensing. The NiCo 2 O 4 was prepared by a facile hydrothermal reaction and subsequently treated in a commercial microwave oven to eliminate the residual water introduced during the hydrothermal procedure. Structural analysis showed that there was no significant structural alteration before and after microwave treatment. The elimination of water residuals was confirmed by the stoichiometric ratio change by using element analysis. The microwave treated NiCo 2 O 4 (M-NiCo 2 O 4) showed excellent performance as a glucose sensor (sensitivity 431.29 µA•mmol/L −1 •cm −2). The sensing performance decreases dramatically by soaking the M-NiCo 2 O 4 in water. This result indicates that the introduction of residual water during hydrothermal process strongly affects the electrochemical performance and microwave pre-treatment is crucial for better sensory performance.

NiCo2O4 Nano-/Microstructures as High-Performance Biosensors: A Review

“…Dry rod-like NiCo 2 O 4 synthesized through a facile hydrothermal reaction followed by subsequently microwave treatment. The non-enzymatic glucose sensor fabricated using these rod-like features showed a high sensitivity of 431.29 µA mM −1 cm −2 [ 238 ]. The microwave treatment completely removed the water and made the material highly porous for exhibiting excellent biosensing applications.…”

“…Numerous studies have been conducted to verify the selectivity of the NiCo 2 O 4 -based modified sensors as ascorbic acid, dopamine, and uric acid coexist along with glucose in human blood serum [ 272 ]. Therefore, for practical applications, these components should not affect the amperometric parameters and the positive results have been reported [ 230 , 237 , 238 , 241 , 247 , 272 , 273 ]. Additionally, reproducibility and stability of the modified NiCo 2 O 4 -based electrodes have been analyzed.…”