Dual Catalytic Systems for Consecutive Isomerization-Hydroformylation Reactions

Abstract

A concept for the homogeneous hydroformylation of internal olefins to linear aldehydes is presented. The internal olefin is isomerized to its terminal isomer by one catalyst prior to hydroformylation by a second transition metal catalyst. The terminal olefins obtained by isomerization react preferentially to give linear aldehydes. The viability of the concept is demonstrated by a dual catalytic Ru/Rh system with chelating phosphanophosphite ligands. Thus, the isomerization ± hydroformylation sequence represents a promising starting point for the economically important refinement of internal olefins.

Recent Advances on Chemo-, Regio- and Stereoselective Hydroformylation

“…17 Related investigations were performed by BASF, which reported the hydroformylation of methyl pent-3-enecarboxylate (115) with [Rh(CO) 2 acac] and 118 as ligand. Methyl 5formylvalerate (116) was formed with 72% selectivity (Scheme 26). 115…”

Synthesis, characterization, reactivity and theoretical studies of ruthenium carbonyl complexes containing ortho-substituted triphenyl phosphanes

“…Ruthenium compounds with phosphane ligands are known to have applications in various fields of catalysis, including hydrogenation [7][8][9], isomerization [10][11][12][13][14] and hydroformylation reactions [15][16][17][18]. Although ruthenium-phosphanes are well-known systems, they are still of interest.…”

Total Synthesis of a Glycoglycerolipid from Meiothermus taiwanensis through a One‐Pot Glycosylation Reaction and Exploration of its Immunological Properties

“…Thus, overall, the single component Rh‐biphephos catalyst proved quite effective for this tandem isomerization‐hydroformylation. Noteworthy, alternative strategies to overcome the isomerization problem, relying on the use of a dual catalytic system – Rh for hydroformylation/Ru for isomerization – such as described by Beller et al 21. and by Nozaki et al.,22 proved ineffective in our case.…”