Dual-Energy Computed Tomography of the Liver: Uses in Clinical Practices and Applications

Tsurusaki, Masakatsu; Sofue, Keitaro; Hori, Masatoshi; Sasaki, Kosuke; Ishii, Kazunari; Murakami, Takamichi; Kudo, Masatoshi

doi:10.3390/diagnostics11020161

Cited by 19 publications

(16 citation statements)

References 62 publications

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“…Dual-energy computed tomography (DECT) is a promising approach in the evaluation of liver lesions. Based on CT data at two different energy spectra, DECT can yield several types of images including virtual monoenergetic imaging, effective atomic number map, iodine map and so on, which is particularly useful to improve iodine contrast visualization and quantitatively reflect the blood flow [ 23 ]. DECT increases the accuracy in the differentiation between benign and malignant hepatic lesions through iodine quantification [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Imaging features of biliary adenofibroma of the liver with malignant transformation: a case report with literature review

Zhao

Liu

et al. 2022

BMC Med Imaging

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Background Biliary adenofibroma (BAF) is a rare primary hepatic tumor with the potential risk of malignant transformation. Given the extreme rarity of the disease, the imaging features of BAF are unclear. We presented a case of malignant BAF and conducted a systematic literature review. We highlighted the key imaging features in the diagnosis and aggressiveness assessment of BAF, as well as the role of various imaging modalities in evaluating BAF. Case presentation We reported a 64-year-old woman with a 5-months history of pain in the right upper quadrant abdomen. US of the liver showed a hypoechoic subcapsular nodule. CT scan revealed a subcapsular solid-cystic mass in segment V of the liver. The mass showed a marked enhancement in the arterial phase followed by wash-out in the venous phase. The patient underwent partial resection of liver’s right lobe. The mass was diagnosed as BAF with malignant transformation by postoperative pathology. Conclusions CT and MRI are helpful in recognizing and characterizing BAF. The imaging features of BAF include a solitary, large solid-cystic mass with a well-defined margin, lobulated shape, and internal septa; subcapsular location; no intrahepatic bile duct communication; the presence of von Meyenberg complexes in background liver. The enhancement patterns may have the potential to assess the aggressiveness of BAF, and that marked enhancement in the arterial phase followed by wash-out in the venous phase is suggestive of malignant BAF.

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Section: Discussionmentioning

confidence: 99%

Imaging features of biliary adenofibroma of the liver with malignant transformation: a case report with literature review

Zhao

Liu

et al. 2022

BMC Med Imaging

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“…Dual-energy CT (DECT), a relatively new imaging technology, allows characterization of tissue composition, such as calcium, iodine, and fat, and improves detection of pathologies by using two X-ray beams of different kVp energies [ 30 , 31 ]. One of the stated benefits of DECT over conventional CT scan can be better characterization of small hypoattenuating liver lesions (cysts vs. LM) using iodine images.…”

Section: Discussionmentioning

confidence: 99%

Can preoperative liver MRI with gadoxetic acid help reduce open-close laparotomies for curative intent pancreatic cancer surgery?

et al. 2021

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Objectives To evaluate gadoxetic acid-enhanced liver MRI (EOB-MRI) versus contrast-enhanced computed tomography (CECT) for preoperative detection of liver metastasis (LM) and reduction of open-close laparotomies for pancreatic ductal adenocarcinoma (PDAC). Methods Sixty-six patients with PDAC had undergone preoperative EOB-MRI and CECT. LM detection by EOB-MRI and CECT and their impact on surgical planning, open-close laparotomies were compared by clinical and radiology reports and retrospective analysis of imaging by two blinded independent readers. Histopathology or imaging follow-up was the reference standard. Statistical analysis was performed at patient and lesion levels with two-sided McNemar tests. Results EOB-MRI showed higher sensitivity versus CECT (71.7% [62.1-80.0] vs. 34% [25.0-43.8]; p = 0.009), comparable specificity (98.6%, [96.9-99.5] vs. 100%, [99.1-100], and higher AUROC (85.1%, [80.4-89.9] vs. 66.9%, [60.9-73.1]) for LM detection. An incremental 7.6% of patients were excluded from surgery with a potential reduction of up to 13.6% in futile open-close laparotomies due to LM detected on EOB-MRI only. Conclusions Preoperative EOB-MRI has superior diagnostic performance in detecting LM from PDAC. This better informs surgical eligibility with potential reduction of futile open-close laparotomies from attempted curative intent pancreatic cancer surgery.

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“…DECT is based on CT data acquisition by using X-rays generated at two different energy spectra; therefore, allowing for superior materials discrimination and characterization. Images are obtained either with dual-source, ultra-fast kV switching, or sandwich detector[ 6 , 16 ]. Then, DECT data post-processing generates several types of images: monochromatic image reconstructions, useful to improve iodine contrast visualization; attenuation maps of different elements according to their atomic number, including iodine, calcium, and water[ 6 ].…”

Section: Imaging Techniquesmentioning

confidence: 99%

Liver involvement in patients with COVID-19 infection: A comprehensive overview of diagnostic imaging features

Ippolito¹,

Maino²,

Vernuccio³

et al. 2023

World J Gastroenterol

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During the first wave of the pandemic, coronavirus disease 2019 (COVID-19) infection has been considered mainly as a pulmonary infection. However, different clinical and radiological manifestations were observed over time, including involvement of abdominal organs. Nowadays, the liver is considered one of the main affected abdominal organs. Hepatic involvement may be caused by either a direct damage by the virus or an indirect damage related to COVID-19 induced thrombosis or to the use of different drugs. After clinical assessment, radiology plays a key role in the evaluation of liver involvement. Ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI) may be used to evaluate liver involvement. US is widely available and it is considered the first-line technique to assess liver involvement in COVID-19 infection, in particular liver steatosis and portal-vein thrombosis. CT and MRI are used as second- and third-line techniques, respectively, considering their higher sensitivity and specificity compared to US for assessment of both parenchyma and vascularization. This review aims to the spectrum of COVID-19 liver involvement and the most common imaging features of COVID-19 liver damage.

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Dual-Energy Computed Tomography of the Liver: Uses in Clinical Practices and Applications

Cited by 19 publications

References 62 publications

Imaging features of biliary adenofibroma of the liver with malignant transformation: a case report with literature review

Imaging features of biliary adenofibroma of the liver with malignant transformation: a case report with literature review

Can preoperative liver MRI with gadoxetic acid help reduce open-close laparotomies for curative intent pancreatic cancer surgery?

Liver involvement in patients with COVID-19 infection: A comprehensive overview of diagnostic imaging features

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