Dual Functional Fluorescent Chemosensor for Discriminative Detection of Ni²⁺ and Al³⁺ Ions and Its Imaging in Living Cells

Abstract

A binaphthyl derived fluorescent probe (S)-1 was developed for dual channel detection of Ni 2+ and Al 3+ ions. The sensing of Ni 2+ and Al 3+ ions takes place by two pathways: (i) fluorescent turn-on response via the blocking of the photoinduced electron transfer process and (ii) red-shifted fluorescent enrichment via the intramolecular charge transfer process. All these findings were supported by NMR, mass spectrometry, and theoretical studies. In addition, sensing of Al 3+ ions was successfully applied into live cells for bioimaging studies and logic gate applications.

Multifunctional Nanohybrid of Palladium Nanoparticles Encapsulated by Carbon‐Dots for Exploiting Synergetic Applications

“…The slope was obtained from the linear plot as shown in Figure c, thereby the detection limit of Ni 2+ was calculated to be 7.26 × 10 −9 m . The lower detection limit for Ni 2+ obtained with Pd/C‐dots fluorescence probe showed much better than or comparable to those obtained by other fluorescence‐based sensors (Table S1, Supporting Information) …”

Donor (HO-) and Acceptor (Nitro-) Substituted BODIPY as a Solvent Turn-on Fluorescence Dye

“…[9][10][11][12][13][14][15][16][17] The distinctive structural characteristics of nitro-BODIPY molecules are the electron donating and electron accepting chromophores in the same molecule by π-conjugation involving single or double bonds. BODIPY core of acceptor-BODIPY types, in contrast, are electron deficient owing to electron withdrawing substituents that takes electron by PET (photoinduced electron transfer) mechanism, [18,19] which implies BODIPY core losing its fluorescing ability, the dilemma of nitrophenyl BODIPY and nitroarene dyes. [20,21] Common but very unique strategy with several reports is the PET blocking electron transfer (ET) mechanism, which stops PET to acceptor in fluorophore-acceptor conjugates due to lowering energy of the fluorophore LUMO as consequent of intermolecular interactions.…”

Using calculations of the electronically excited states for investigation of fluorescent sensors: A review

“…[7][8][9] Fluorescent sensor is called a chemosensor when its reaction with a specific analyte is reversible. [10][11][12] However, if the fluorescent sensor participates irreversibly with a specific analyte, then it is called a chemodosimeter. [13][14][15] The first fluorescent sensor based on spirolactam ring-opening process of rhodamine B derivative for the detection of Cu(II) ions was reported by Czarnik in 1992.…”

“…Especially, they can be used to monitor substances in living cells. [12,17,18] Currently, quantum chemical calculations have been strongly developed and used to predict and explain the biological and chemical processes. The likelihood and products of chemical reactions, as well as structural features, the properties of electrons, and the nature of the bonding in compounds... were predicted and elucidated by quantum chemical calculations.…”