Dual inhibition of sirtuins 1 and 2: reprogramming metabolic energy dynamics in chronic myeloid leukemia as an immunogenic anticancer strategy

Schnekenburger, Michael; Lorant, Anne; Gajulapalli, Sruthi Reddy; Rajora, Ridhika; Lee, Jin‐Young; Mazumder, Aloran; Yang, Haeun; Christov, Christo; Kang, Hyoung Jin; Pirotte, Bernard; Diederich, Marc

doi:10.1002/cac2.12590

Cancer Communications

2024

DOI: 10.1002/cac2.12590

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Dual inhibition of sirtuins 1 and 2: reprogramming metabolic energy dynamics in chronic myeloid leukemia as an immunogenic anticancer strategy

Michael Schnekenburger,

Anne Lorant,

Sruthi Reddy Gajulapalli

et al.

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Preparation and pharmacological characterization of the enantiomers of the anticancer agent R/S-N-3-cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea: Identification of the R-enantiomer as the active eutomer

Schnekenburger,

Goffin,

Schoumacher

et al. 2025

European Journal of Medicinal Chemistry Reports

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Preparation and pharmacological characterization of the enantiomers of the anticancer agent R/S-N-3-cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea: Identification of the R-enantiomer as the active eutomer

Schnekenburger,

Goffin,

Schoumacher

et al. 2025

European Journal of Medicinal Chemistry Reports

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Dual inhibition of sirtuins 1 and 2: reprogramming metabolic energy dynamics in chronic myeloid leukemia as an immunogenic anticancer strategy

Cited by 1 publication

References 10 publications

Preparation and pharmacological characterization of the enantiomers of the anticancer agent R/S-N-3-cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea: Identification of the R-enantiomer as the active eutomer

Preparation and pharmacological characterization of the enantiomers of the anticancer agent R/S-N-3-cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea: Identification of the R-enantiomer as the active eutomer

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