Dual role of tannic acid and pyrogallol incorporated in plaster of Paris: Morphology modification and release for antimicrobial properties

Kharouf, Naji; Mancino, Davide; Zghal, Jihed; Hellé, Sophie; Jmal, Hamdi; Lenertz, Marc; Viart, N.; Bahlouli, Nadia; Meyer, Florent; Haïkel, Youssef; Ball, Vincent

doi:10.1016/j.msec.2021.112209

Cited by 14 publications

(26 citation statements)

References 35 publications

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“…Indeed, those authors reported that the numbers and positions of substitutions in the benzene rings of the phenolic acids, along with the saturated side-chain lengths, influenced antimicrobial properties of the phenolic acids against different microorganisms. The antibacterial effects of PY incorporated into dental adhesive (adhesive-resin with acidic function monomers) against Streptococcus mutans and its effects against Staphylococcus aureus when incorporated into plaster of Paris were previously reported [16,21]. Moreover, the antibacterial properties of resveratrol against various bacteria, including E. faecalis, were also reported in a previous study [26].…”

Section: Discussionmentioning

confidence: 82%

“…Both antibacterial tests (DCT and ADT) showed great antibacterial efficacy for the sealer doped with 5%PY as well as a peculiar brown-colored zone in the agar (Figure 1b). The brown color observed during the study with the experimental material was probably induced by oxidation of the pyrogallol in the bacterial medium [16,21].…”

Section: Discussionmentioning

confidence: 92%

“…The antioxidant activity of OB doped with the tested polyphenols was evaluated using the DPPH discoloration method [16]. OB@5%PY presented increased and more rapid antioxidant activity than OB@5%RS.…”

Section: Discussionmentioning

confidence: 99%

“…RS has been used to treat dentin before the application of dental adhesives in order to preserve the dentin-resin bond over time [14]. Moreover, pyrogallol (PY) (1,2,3-trihydroxybenzene) is a well-known organic compound produced in plants [15] that is often used for its potent antibacterial activity against Staphylococcus aureus [16]. PY has been used in endosseous implant applications as a nanocoating; the release of PY can reduce significantly the growth of planktonic bacteria [17].…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, the presence of pyrogallol groups in tannic acid have been demonstrated to play a role in the treatment of dentin hypersensitivity [18]. Several studies reported that resveratrol and pyrogallol exhibit antibacterial activity against Gramand Gram+ bacteria [16,[19][20][21].…”

Section: Introductionmentioning

confidence: 99%

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Impacts of Resveratrol and Pyrogallol on Physicochemical, Mechanical and Biological Properties of Epoxy-Resin Sealers

et al. 2022

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This study aimed at evaluating the physicochemical and biological properties of experimental epoxy-resin sealers containing polyphenols such as resveratrol and pyrogallol. A conventional epoxy resin (OB) was modified by adding different concentrations of resveratrol (RS) or pyrogallol (PY) to its composition. Antibacterial and antioxidant activities, mechanical properties, along with wettability and morphological changes were investigated. The results were statistically analyzed using ANOVA and multiple comparison tests (α = 0.05). The incorporation of the tested polyphenols into the epoxy resin enhanced its mechanical properties. PY demonstrated much better antioxidant and antibacterial activities than RS, which were associated with a higher release of PY. In contrast, PY showed a higher cytotoxicity than OB and OB doped with RS. OB containing PY presented a rougher surface and higher water absorption than OB doped with RS. Both tested polyphenols caused no notable changes to the overall porosity of OB. Resveratrol and pyrogallol may not only influence the morphology and mechanical properties of epoxy-resin sealers, but could also enhance antioxidant activity and antibacterial effects against Enterococcus faecalis. Most epoxy-resin sealers currently available in the market can be considered as “passive” materials. Thus, doping their composition with specific polyphenols may be a suitable strategy to confer some antibacterial properties, antioxidant potential, along with improvement of some mechanical properties.

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Impacts of Resveratrol and Pyrogallol on Physicochemical, Mechanical and Biological Properties of Epoxy-Resin Sealers

et al. 2022

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A Biodegradable Supramolecular Adhesive with Robust Instant Wet Adhesion for Urgent Hemostasis and Wound Repair

Guo,

Zhang,

Jia

et al. 2024

Adv Funct Materials

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Surgical adhesives are crucial for achieving rapid hemostasis and immediate wound management during clinical interventions. However, developing a tissue adhesive that combines instant adhesive strength with biodegradability in dynamic, wet, or hemorrhagic biological environments remains a persistent challenge. Here, a biodegradable supramolecular tissue adhesive with robust instant adhesion to wet tissue surfaces within 5 s is presented. The distinctive synergy of surface‐rich adhesive groups and the hydrophobic main chain enables the adhesive to surmount the hydration layer on the tissue surface, ensuring rapid adhesion. Importantly, the internal structure of this supramolecular adhesive significantly contributes to its exceptional holding adhesion strength. Additionally, in vivo experiments using a rat liver incision model and a skin injury model are conducted. These experiments demonstrate its effectiveness in emergency hemostasis and wound management. Consequently, this supramolecular tissue adhesive exhibits significant potential in surgical applications, addressing critical needs in urgent clinical scenarios and potentially making valuable contributions to the medical field.

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3D-printing of alginate/gelatin scaffold loading tannic acid@ZIF-8 for wound healing: In vitro and in vivo studies

Maghsoudi,

Aghdam,

Asbagh

et al. 2024

International Journal of Biological Macromolecules

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Dual role of tannic acid and pyrogallol incorporated in plaster of Paris: Morphology modification and release for antimicrobial properties

Cited by 14 publications

References 35 publications

Impacts of Resveratrol and Pyrogallol on Physicochemical, Mechanical and Biological Properties of Epoxy-Resin Sealers

Impacts of Resveratrol and Pyrogallol on Physicochemical, Mechanical and Biological Properties of Epoxy-Resin Sealers

A Biodegradable Supramolecular Adhesive with Robust Instant Wet Adhesion for Urgent Hemostasis and Wound Repair

3D-printing of alginate/gelatin scaffold loading tannic acid@ZIF-8 for wound healing: In vitro and in vivo studies

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