Dual roles of the hippocampus and intraparietal sulcus in network integration and segregation support scene recognition

Abstract

Effectively recognizing surroundings is a critical ability in human navigation. Previous neuroimaging studies have depicted distributed brain regions underpinning spatial navigation, but little is known about how these regions are formed into the navigation network (NN) supporting scene recognition. In this study, we addressed this issue by using a voxel-based global functional connectivity method to characterize the integration (i.e., within-network connectivity, WNC) of the NN and its segregation (i.e., between-network connectivity, BNC) from non-NN networks. We found that the majority of the voxels in the NN showed a stronger WNC than BNC, indicating the encapsulation of the NN. Importantly, individuals with stronger WNC and weaker BNC in the left hippocampus (Hipp) and intraparietal sulcus (IPS) performed better in scene recognition, suggesting that the left Hipp and IPS were involved in scene recognition by both integrating regions in the NN and separating the NN from non-NN networks. Further analyses showed that the integration of these two regions in the NN serves different functions, that is, while the WNC of the left Hipp was only related to scene recognition, the WNC of the left IPS was also related to the general executive control function of attention. In short, our study demonstrated the dual roles of the Hipp and IPS in integration and segregation of the NN to support scene recognition, suggesting that scene recognition involves not only regions specialized in spatial navigation, but also those with general functions.

Dissociation of categorical and coordinate spatial relations on dynamic network organization states

“…In contrast, the competitive interactions between the ventral and other subnetworks are important for precise representation of coordinate spatial relations. In line with this result, we have found in a previous study that stronger integration of the IPS with other regions in the navigation network was associated with poor ability of executive control ( Hao et al, 2017 ). Thus, we speculated that competitive interactions between the ventral and parietal-frontal subnetworks might be related to better ability of executive control or other high-level cognitive functions, which brings better representation of coordinate spatial relations.…”

“…Then, we averaged the reaction times (RTs) of the correct trials for each participant. For visualization and enhancing readability, we converted these RTs into speed values using the classic formula: speed i = (Max–RT i )/(Max–Min), where i refer to each participant, and Max and Min correspond to the maximum and minimum RT across all participants ( Hao et al, 2017 ). The speed values were used as the ordinal scene recognition scores.…”

Can abacus course eradicate developmental dyscalculia

“…This is not surprising as the IPS is reported to support domain-specific numerical processing (Wei et al, 2014;H. Zhang et al, 2012), spatial ability (Hao et al, 2018;Schel & Klingberg, 2017), as well as domain-general working memory (Attout et al, 2014;Silk et al, 2010) and attention ability (Fan et al, 2018;Sahan et al, 2019). Cognitive studies have treated DD as a heterogeneous disorder relating to deficits in numberspecific processing or domain-general processing.…”