2023
DOI: 10.3390/biom13061011
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Dual-Step Controlled Release of Berberine Hydrochloride from the Trans-Scale Hybrids of Nanofibers and Microparticles

Abstract: In this nano era, nanomaterials and nanostructures are popular in developing novel functional materials. However, the combinations of materials at micro and macro scales can open new routes for developing novel trans-scale products with improved or even new functional performances. In this work, a brand-new hybrid, containing both nanofibers and microparticles, was fabricated using a sequential electrohydrodynamic atomization (EHDA) process. Firstly, the microparticles loaded with drug (berberine hydrochloride… Show more

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Cited by 33 publications
(22 citation statements)
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“…Processability plays a pivotal role in the commercialisation of MOPs, enabling the expansion of their potential applications and enhancing their overall performance. 81,82 Therefore, we tested the potential processability of Ag 2 O@UMOPs. As shown in Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Processability plays a pivotal role in the commercialisation of MOPs, enabling the expansion of their potential applications and enhancing their overall performance. 81,82 Therefore, we tested the potential processability of Ag 2 O@UMOPs. As shown in Fig.…”
Section: Resultsmentioning
confidence: 99%
“…In further study, lower cost for AP‐based encapsulation systems is worth considering in industry production. Furthermore, new kinds of pharmaceutical excipients are always highly desired (Weiss et al., 2006; Zhou, Wang, et al., 2023). The foodborne components are important sources as demonstrated here.…”
Section: Resultsmentioning
confidence: 99%
“…Electrospinning of natural and synthetic polymers is a scalable and cost-effective method to obtain flexible nonwoven nanofibers having different functional structures such as core–shell, trilayer core–shell, core–shell with a Janus core, Janus, and monolithic hybrids for different kinds of medical and wound-dressing applications. The electrospinning process allows the large-scale production of functional materials and the creation of therapeutic agent-loaded complex nanostructures for the delivery of active materials representing two directions of electrospinning. , However, a combination of different electrospinning techniques can enrich the existing method for creating more and more functional nanomaterials . In the healing process of large wounds and skin injuries such as burns and abrasions, these membranes are commonly applied .…”
Section: Introductionmentioning
confidence: 99%
“…The nanofibrous structure increases skin growth. If incorporated within the fibers, a drug , or antibacterial NPs can be discharged into the curative wound in a regulated and homogeneous way. , These promising characteristics make electrospun membranes ideal platforms for developing new hybrid materials for rapid wound healing and antimicrobial effects. , …”
Section: Introductionmentioning
confidence: 99%
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