Dual use of cigarettes and electronic nicotine delivery systems during pregnancy and the risk of small for gestational age neonates

Cárdenas, Víctor; Ali, Mir M.; Fischbach, Lori; Nembhard, Wendy N.

doi:10.1016/j.annepidem.2020.08.002

Cited by 23 publications

(37 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although previous studies have highlighted evidence of increased risk of adverse birth outcomes such as small-for-gestational-age, low birthweight, and preterm birth, with exposure to tobacco through vaping [ 54 – 56 ], we did not observe any associations between vaping and preterm birth, gestation, or birthweight. This could be attributed to various factors: for example, our study had a comparatively small number of women reporting vaping, resulting in relatively lower power to identify associations.…”

Section: Discussioncontrasting

confidence: 99%

Electronic cigarette use (vaping) and patterns of tobacco cigarette smoking in pregnancy–evidence from a population-based maternity survey in England

et al. 2021

View full text Add to dashboard Cite

Objectives Exposure to tobacco products during pregnancy presents a potential harm to both mother and baby. This study sought to estimate the prevalence of vaping during pregnancy and to explore the factors and outcomes associated with vaping in pregnancy. Setting England. Participants Women who gave birth between 15th and 28th October 2017. Methods A cross-sectional population-based postal survey of maternal and infant health, the National Maternity Survey (NMS) 2018. The prevalence of vaping and patterns of cigarette smoking were estimated, and regression analysis was used to explore associations between maternal characteristics and vaping, and between vaping and birth outcomes. Outcome measures Unweighted and weighted prevalence of vaping with 95% confidence intervals, and unadjusted and adjusted relative risks or difference in means for the association of participant characteristics and secondary outcomes with vaping. Secondary outcome measures were: preterm birth, gestational age at birth, birthweight, and initiation and duration of breastfeeding. Results A total of 4,509 women responded to the survey. The prevalence of vaping in pregnancy was 2.8% (95%CI 2.4% to 3.4%). This varied according to the pattern of cigarette smoking in pregnancy: 0.3% in never-smokers; 3.3% in ex-smokers; 7.7% in pregnancy-inspired quitters; 9.5% in temporary quitters; and 17.7% in persistent smokers. Younger women, unmarried women, women with fewer years of formal education, women living with a smoker, and persistent smokers were more likely to vape, although after adjusting for pattern of cigarette smoking and maternal characteristics, persistent smoking was the only risk factor. We did not find any association between vaping and preterm birth, birthweight, or breastfeeding. Conclusions The prevalence of vaping during pregnancy in the NMS 2018 was low overall but much higher in smokers. Smoking was the factor most strongly associated with vaping. Co-occurrence of vaping with persistent smoking has the potential to increase the harms of tobacco exposure in pregnant women and their infants.

show abstract

Section: Discussioncontrasting

confidence: 99%

Electronic cigarette use (vaping) and patterns of tobacco cigarette smoking in pregnancy–evidence from a population-based maternity survey in England

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Previous studies typically assumed that dual users are a homogeneous group when evaluating their effects on pregnancy outcomes. 21 In contrast, we acknowledged that dual users may include both habitual heavy smokers who occasionally vape and vapers who only occasionally smoke, leading to different risks of adverse pregnancy outcomes.…”

Section: Discussionmentioning

confidence: 96%

Exposure-response analysis of the association of maternal smoking and use of electronic cigarettes (vaping) in relation to preterm birth and small-for-gestational-age in a national US sample, 2016-2018

Wang

Burstyn

2021

Preprint

View full text Add to dashboard Cite

We aimed to estimate exposure-response associations between smoking or vaping, and preterm and small-for-gestational age (SGA) births. We included 99,201 mothers who delivered live singletons in 2016-2018 from the Pregnancy Risk Assessment Monitoring System. We created exposure categories based on participants' self-reported average number of cigarettes smoked per day and vaping frequency. Dual users in late pregnancy were a heterogeneous group: 36% heavily smoked and occasionally vaped; 29% lightly smoked and frequently vaped; 19% lightly smoked and frequently vaped; and 15% both heavily smoked and frequently vaped. While dual users who heavily smoked and occasionally vaped had the highest adjusted OR for SGA (3.4, 95% CI 1.7-6.6), all the dual users were on average at about twice the odds of having SGA than non-users. While the risks of preterm birth were higher among sole light smokers (adjusted OR 1.3, 95% CI 1.1-1.5) and sole heavy smokers (adjusted OR 1.4. 95 CI 1.2-1.8) than non-users, the adjusted odds of preterm births for dual users were not noticeably higher than those of non-users, unless they were also heavy smokers. Excess of preterm births among heavy vapers was suggested. Among younger non-Hispanic white women (where vaping is most common), only excess risk of SGA, not preterm, with vaping was apparent. Relative to non-users, both smoking and vaping during pregnancy appear to increase risk of SGA, but excess risk of preterm births appears to be primarily attributable to smoking alone. Higher levels of exposure tended to confer more risk.

show abstract

“…Smoking only e-cigarettes in the last trimester of pregnancy [19] No e-cigarettes or traditional cigarettes in the last trimester of pregnancy Cardenas et al 2020 Pre-pregnancy trimester and last trimester e-cigarette only [20] No traditional cigarettes or e-cigarettes in pre-pregnancy…”

Section: Kim Et Al 2020mentioning

confidence: 99%

Association of E-Cigarette Use during Pregnancy with Adverse Birth Outcomes: A Meta-Analysis

Ren¹,

Yao²,

Ma³

2022

Proceedings of the 4th International Conference on Statistics: Theory and Applications

View full text Add to dashboard Cite

With the increasing growth of the global e-cigarette market, more and more pregnant women use e-cigarettes as a safe alternative to traditional cigarettes. However, several studies have shown that e-cigarettes damage the human respiratory and cardiovascular systems and that nicotine is a risk factor for fetal development. To determine the association between e-cigarette use during pregnancy and adverse birth outcomes in pregnant women, we conducted a meta-analysis to assess the present evidence's strength. 735 studies were screened through PubMed, Web of Science, and Scopus databases. A total of nine articles met the inclusion criteria of this paper, and six articles were conducted for a meta-analysis after excluding studies with high heterogeneity. The six studies were further divided into two subgroups based on their differences in study types and population samples: one subgroup was three national case-control studies based on the United State Pregnancy Risk Assessment Monitoring System (PRAMS) database, and the other included three small-scale regional studies. The small for gestational age (SGA) was identified as the indicator for assessing the association between e-cigarette use and adverse birth outcomes in pregnant women. We found a significant association of pregnant women using ecigarettes during pregnancy with SGA (OR = 1.32, 95%CI = 1.03, 1.69). Low heterogeneity of multiple studies (I 2 =32%) and low publication bias as indicated by funnel plots. Our research proves that the risks of e-cigarette use during pregnancy to the unborn child are evident. Therefore, pregnant women need to be advocated to reduce their use of e-cigarettes during pregnancy.

show abstract

Dual use of cigarettes and electronic nicotine delivery systems during pregnancy and the risk of small for gestational age neonates

Cited by 23 publications

References 50 publications

Electronic cigarette use (vaping) and patterns of tobacco cigarette smoking in pregnancy–evidence from a population-based maternity survey in England

Electronic cigarette use (vaping) and patterns of tobacco cigarette smoking in pregnancy–evidence from a population-based maternity survey in England

Exposure-response analysis of the association of maternal smoking and use of electronic cigarettes (vaping) in relation to preterm birth and small-for-gestational-age in a national US sample, 2016-2018

Association of E-Cigarette Use during Pregnancy with Adverse Birth Outcomes: A Meta-Analysis

Contact Info

Product

Resources

About