We developed a tool based on a modified number pad to empower persons with certain diseases, in particular of neuromuscular origin, to efficiently operate a computer and enter text. As the keypad lies securely in both hands, the system is ideal for someone who has motor problems using a full-size keyboard. The software offers various assistive techniques. For example, text entry is facilitated with the help of word prediction, and an ambiguous mode with word-level disambiguation allows text entry using the entire Latin alphabet with six keys. In addition to describing the system, we analyze the ambiguous mode and the influence of dictionary size. Initial empirical results with the system, which is already in operation, indicate that it indeed represents a viable alternative by decreasing effort without increasing the time to operate a computer. This journal article mainly differs from the related proceedings paper through an extended literature review and analyses regarding dictionary size.