“…The monitoring of such drug is important for quality assurance in preparations and for obtaining optimum therapeutic concentrations. For its measurement, several methods have been reported, such as spectrophotometry [8], thin-layer chromatography [9,10], spectrofluorimetry [11], gas chromatography (GC) with electron capture detection [12], high-performance liquid chromatography (HPLC) with UV [10,13,14], electrochemical [15,16] or mass spectrometric detection [10,17]. However, most of them have one or more drawbacks.…”