Duodenum preserving pancreatectomy in chronic pancreatitis: Design of a randomized controlled trial comparing two surgical techniques [ISRCTN50638764]

Köninger, Jörg; Seiler, Christoph M.; Wente, Moritz N.; Reidel, M.; Gazyakan, Emre; Mansmann, Ulrich; Müller, Michael; Frieß, Helmut; Büchler, Markus W.

doi:10.1186/1745-6215-7-12

Cited by 19 publications

(10 citation statements)

References 24 publications

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“…These findings were supported by another study by Andersen and Topazian [55]. An RCT is ongoing to compare this procedure with other forms of DPPHR (Beger and Frey), and the reports are awaited [56].…”

Section: Resectional Proceduressupporting

confidence: 62%

Surgery for Chronic Pancreatitis

Perwaiz¹,

Singh²,

Chaudhary³

2011

Indian J Surg

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Chronic pancreatitis (CP) is progressive inflammatory process of the pancreas. Abdominal pain remains the most debilitating symptom affecting quality of life, apart from diabetes mellitus, steatorrhoea and weight loss. The treatment options have evolved over the past decades and are aimed to provide durable relief in pain with possible attempt to support or improve the failing endocrine and exocrine functions. Surgical treatment options have shown the potentials to provide superior long term results compared to the pharmacological and endoscopic modalities and are broadly divided in to drainage, resection and combination hybrid procedures. The choice is based on the morphology of the main pancreatic duct, presence of head mass and associated complication of CP. Knowing the basic nature of the disease, total pancreatectomy seems a curative option but not without significant morbidities. There is recent paradigm shift towards organ sparing surgical procedures with reasonable success. Despite recent advancement in the treatment modalities for CP the overall quality of life remains moderate which need further addressal.

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Section: Resectional Proceduressupporting

confidence: 62%

Surgery for Chronic Pancreatitis

Perwaiz¹,

Singh²,

Chaudhary³

2011

Indian J Surg

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“…Some believe (minimal) resection should be part of any surgical procedure for CP, whereas others generally do not perform resection. 11,12 The argument against drainage without resection is that these patients would be insufficiently treated, leading to early recurrence of pain. On the contrary, another recent study suggested that patients selected for a PD drainage procedure have a better postoperative QoL than those undergoing resectional procedures.…”

mentioning

confidence: 99%

Functional and Medical Outcomes After Tailored Surgery for Pain Due to Chronic Pancreatitis

Gaag¹,

Gulik²,

Busch³

et al. 2012

Annals of Surgery

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“…Subsequently, both the opened pancreatic and common bile ducts were included in the end-to-side anastomosis of the pancreatic head with an interposed jejunal loop [22]. The LPJ-a major part of the Frey procedure-was omitted [22][23][24].…”

Section: Pancreatic Operationsmentioning

confidence: 99%

“…The Bern modification of DPPHR is used to try to combine the advantages of the Beger and Frey/Smith procedures and consists of a central pancreatic head resection without transsection of the pancreas, whereas the LPJ-a major part of the Frey procedure-is omitted [22][23][24].…”

mentioning

confidence: 99%