Dural metastasis in patients with malignant neoplasm and chronic subdural hematoma

Tseng, Sheng Hong; Liao, Chi-Yu; Lin, San; Chen, Y.; Shun, Chia‐Tung

doi:10.1034/j.1600-0404.2003.00080.x

Cited by 36 publications

(31 citation statements)

References 13 publications

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“…Cancer is an uncommon cause of SDH, with less than 100 cases reported in the literature [2][3][4][5][6][7][8]. Imbalances between blood coagulation and fibrinolysis and/or thrombocytopenia resulting from advanced cancer are presumed pathomechanisms of SDH in such patients [1][2][3][4][5].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Imbalances between blood coagulation and fibrinolysis and/or thrombocytopenia resulting from advanced cancer are presumed pathomechanisms of SDH in such patients [1][2][3][4][5]. The most frequent cancer types associated with SDH include gastric, prostate, lung, and leukemia [2][3][4][5][6][7][8], all of which are relatively common among geriatric population. By contrast, SDH associated with angiosarcoma is extremely rare: despite vigorous literature search, we could identify only two previous cases [11,12]: in one case, an angiosarcoma originated from the skull [11], and in the other case, the tumor originated from the scalp [12].…”

Section: Discussionmentioning

confidence: 99%

“…There seems to be a difference between SDH caused by angiosarcomas and that caused by other common cancers in the clinical presentation. In the latter, the diagnosis of cancer has almost always been established by the time SDH develops [2][3][4][5][6][7]. By contrast, the diagnosis of angiosarcoma has been made only after surgery for SDH, and diagnostic delay is the rule rather than exception [11,12].…”

Section: Discussionmentioning

confidence: 99%

“…Although cancers metastatic to the skull or dura may cause SDH in rare instances, the presence of underlying cancers has almost always been known for months to years [2][3][4][5][6][7][8]. We experienced a case of skull angiosarcoma manifesting as SDH, posing a diagnostic challenge to physicians because of its rarity and unusual presentation.…”

Section: Introductionmentioning

confidence: 99%

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Subdural Hematoma Caused by Epithelioid Angiosarcoma Originating from the Skull

Yamada

Inamasu

Moriya

et al. 2012

Head and Neck Pathol

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Cancers metastatic to the skull or dura may cause subdural hematoma (SDH). However, the frequency is low, and the presence of underlying cancers has almost always been known in such situations. We report a case of skull angiosarcoma manifesting as SDH, posing a diagnostic challenge to physicians. A 75-year-old man visited our clinic with sensorimotor disturbance of gradual onset approximately 1 month after a minor head trauma. He was diagnosed with SDH after imaging studies, and underwent surgery to evacuate the hematoma. Because the hematoma was organized, surgery was switched from burr-hole drainage to craniotomy. The bone flap as well as the dura over the hematoma had grossly normal appearance, and only the hematoma itself was submitted for histological examination. Although postoperative recovery was uneventful, the patient experienced recurrence of the SDH 2 months after surgery. At the second surgery, the bone flap and dura were intermingled with tumor tissue, and histological examination revealed that an epithelioid angiosarcoma originating from the skull was responsible for the SDH. Timely diagnosis of angiosarcoma manifesting as SDH is difficult because of its rarity. In retrospect, however, the diagnosis might have been established earlier if the bone flap and/or the dura had been biopsied at the time of the first surgery. The present case gives us a lesson that SDH may be an unusual manifestation of malignant tumors of skull or dural origin, and histological examination of not only hematoma capsule but also of the surrounding tissues may provide important diagnostic clues.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Subdural Hematoma Caused by Epithelioid Angiosarcoma Originating from the Skull

Yamada

Inamasu

Moriya

et al. 2012

Head and Neck Pathol

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Cerebrovascular Complications of Cancer

Rogers¹,

Leary²,

Saver

Cancer Neurology in Clinical Practice

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Dural metastases

et al. 2005

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Dural metastases are found at autopsy in 8-9% of patients with advanced systemic cancer. They arise either by direct extension from skull metastases or by hematogeneous spread. Dural metastases are often clinically asymptomatic but they may produce progressive neurological deficits and sometimes subdural hematomas. MRI may be misleading when the metastasis simulates a meningioma or when a subdural hematoma masks the underlying tumor. Whenever possible, surgical removal is the most appropriate treatment. The prognosis is poor because of the progressive systemic cancer but prolonged survival has been reported in operated patients, when the systemic cancer was controlled.

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Dural metastasis in patients with malignant neoplasm and chronic subdural hematoma

Abstract: The results suggest that dural metastasis should be considered in patients with malignant neoplasm and CSH. Further, the prognosis for patients with malignant neoplasm and CSH may be poor because of systemic metastasis and the side-effects of chemotherapy.

Cited by 36 publications

References 13 publications

Subdural Hematoma Caused by Epithelioid Angiosarcoma Originating from the Skull

Subdural Hematoma Caused by Epithelioid Angiosarcoma Originating from the Skull

Cerebrovascular Complications of Cancer

Dural metastases

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