Dynamic Assessment of Light-Induced Vaulting Changes of Implantable Collamer Lens With Central Port by Swept-Source OCT: Pilot Study

González-López, Félix; Mompean, Blas; Bilbao-Calabuig, Rafael; Vila-Arteaga, J.; Beltrán, Jaime; Baviera, Julio

doi:10.1167/tvst.7.3.4

Cited by 53 publications

(54 citation statements)

References 12 publications

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“… 24 , 25 We also found its strength in this study because ICL sizing is also a nonlinear and complex problem. 26 This finding indicates that more accurate ICL vault prediction for ICL sizing can be obtained by combining machine learning models after extensive validation in other datasets. We adopted XGBoost and the stacking ensemble technique, which has been widely used to achieve better performance in many Kaggle competitions and research.…”

Section: Discussionmentioning

confidence: 79%

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens

Kang

Ryu

Lee³

et al. 2021

Trans. Vis. Sci. Tech.

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Selecting the optimal lens size by predicting the postoperative vault can reduce complications after implantation of an implantable collamer lens with a centralhole (ICL with KS-aquaport). We built a web-based machine learning application that incorporated clinical measurements to predict the postoperative ICL vault and select the optimal ICL size. Methods:We applied the stacking ensemble technique based on eXtreme Gradient Boosting (XGBoost) and a light gradient boosting machine to pre-operative ocular data from two eye centers to predict the postoperative vault. We assigned the Korean patient data to a training (N = 2756 eyes) and internal validation (N = 693 eyes) datasets (prospective validation). Japanese patient data (N = 290 eyes) were used as an independent external dataset from different centers to validate the model. Results:We developed an ensemble model that showed statistically better performance with a lower mean absolute error for ICL vault prediction (106.88 μm and 143.69 μm in the internal and external validation, respectively) than the other machine learning techniques and the classic ICL sizing methods did when applied to both validation datasets. Considering the lens size selection accuracy, our proposed method showed the best performance for both reference datasets (75.9% and 67.4% in the internal and external validation, respectively). Conclusions:Applying the ensemble approach to a large dataset of patients who underwent ICL implantation resulted in a more accurate prediction of vault size and selection of the optimal ICL size.Translational Relevance: We developed a web-based application for ICL sizing to facilitate the use of machine learning calculators for clinicians.

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Section: Discussionmentioning

confidence: 79%

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens

Kang

Ryu

Lee³

et al. 2021

Trans. Vis. Sci. Tech.

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“…Thus, the effect of the iris has the net effect of pushing ICL into the lens, followed by a reduction in the central vault. Recently, Kato et al [ 20 ] and Gonzalez-Lopez et al [ 31 ] demonstrated that the ICL vault can be significantly decreased by light-induced pupil constriction. Thus, we speculated that pupil constriction due to the disappearance of the effect of the mydriatic agent played a very important role in vault reduction within 1 day after surgery.…”

Section: Discussionmentioning

confidence: 99%

“…As described previously, the morphology of the crystalline lens has a certain influence on vaulting after ICL implantation. Most recent studies have focused on the effect of the CLR on vaulting after surgery [ 31 , 34 – 36 , 40 ]. However, the measurement of the CLR is relatively complex.…”

Section: Discussionmentioning

confidence: 99%

Short‐term changes in and preoperative factors affecting vaulting after posterior chamber phakic Implantable Collamer Lens implantation

et al. 2021

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Background To describe the very early vault changes in the first month after Implantable Collamer Lens (ICL) implantation and to evaluate the effect of preoperative biometric factors on vault. Methods Eighty-three eyes from eighty-three subjects with complete data who met follow-up requirements were recruited in this retrospective study between May 2019 and March 2020. We quantitatively assessed the postoperative vault at 2 h, 1 day, 1 week, and 1 month following implantation. Associations between the postoperative vault and age, ICL size, spherical equivalent (SE), axial length (AL), central corneal thickness (CCT), flat keratometry (K), steep K, mean K, anterior chamber depth (ACD), crystalline lens thickness (LT), white-to-white (WTW) diameter obtained by three devices, horizontal and vertical sulcus-to-sulcus (STS) diameter, bright and dark pupil sizes (BPS and DPS) and DPS-BPS were investigated using Spearman’s correlation analysis and stepwise multiple regression analysis. Results The mean vault values at 2 h, 1 day, 1 week, and 1 month after ICL implantation were 672.05 ± 30.72, 389.15 ± 28.33, 517.23 ± 30.76 and 530.12 ± 30.22 μm, respectively. Significant differences were found in the vault values at 2 h, 1 day and 1 week after the operation. The ICL size (β = 0.942; p < 0.001), followed by horizontal STS (β = -0.517; p < 0.001), crystalline LT (β = -0.376; p < 0.001) and vertical STS (β = -0.257; p = 0.017), significantly influenced the vault at 1 month after the operation. The multiple regression equation was expressed as follows: central vault (µm) = -1369.05 + 657.121 × ICL size- 287.408 × horizontal STS − 432.497 × crystalline LT − 137.33 × vertical STS (adjusted R2 = 0.643). Conclusions After ICL implantation, the vault decreased and then increased, but it did not return to the vault value 2 h after surgery. The ICL size, horizontal and vertical STS and crystalline LT are key factors for predicting postoperative vaulting.

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“…They found that in myopic-correction with MRSE less than − 6.0 D, the level of accommodation had recovered to their baseline level 3 months postoperatively. Second, during the accommodative reaction in the eye with the ICL lens, except when the lens power changes for a speci c distance, there were other biometric changes (e.g., in the vault and pupil size) occurring [22,23]. The power of the eye may be different from expected if the optic eye system cannot remain static [24].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Accommodation and Accommodative Micro-Fluctuation After Implantable Collamer Lens and LASIK Surgery for Myopia

Zhang²,

Wang

2021

Preprint

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Background: To longitudinally analyze and compare the accommodative micro-fluctuation (MFs) and accommodative function between myopic patients after implantable collamer lens (ICL) implantation and laser in situ keratomileusis (LASIK).Methods: Patients with good corrected visual acuity (20/20 or better) that underwent ICL (V4c) and LASIK for myopic-correction (ranging from -3.50 to -8.50 D) were recruited. Refraction, amplitude of accommodation (AMP), accommodative lags, high-order aberrations (HOAs), and MFs were recorded before surgery and 1 and 3 months after surgery. The ACOMEREF automatic refractor was used to measure the high-frequency component (HFC) of the MFs, which suggested tension of the ciliary muscle.Results: The study comprised 120 eyes. At 3 months after surgery, the manifest refractive spherical equivalent of the ICL and LASIK groups were -0.11 and -0.09 D, respectively (p = 0.46). HFC values were significantly higher at 1 month (p = 0.03) and 3 months postoperatively (p = 0.03) in the ICL group compared to that in the LASIK group. The ocular HOAs of the ICL group was 1.08 ± 0.43 μm, which was lower than the LASIK group 1.45 ± 0.54 μm (p = 0.01). No significant differences in AMP and accommodative lags between groups were noted at 3 months postoperatively. There was a positive correlation between HFC and vault of the ICL lens (r2 = 0.14, p = 0.005). There were no correlations between HFC and HOAs and postoperative MRSE in the two groups (all p﹥0.05).Conclusions: The HFC increased significantly after ICL implantation compared to laser in situ keratomileusis for myopic correction, which indicated increased tension of the ciliary muscle, and had a positive correlation on the vault of the ICL lens; However, studies with longer follow-up time and more structural evaluation are needed.

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Dynamic Assessment of Light-Induced Vaulting Changes of Implantable Collamer Lens With Central Port by Swept-Source OCT: Pilot Study

Cited by 53 publications

References 12 publications

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens

Short‐term changes in and preoperative factors affecting vaulting after posterior chamber phakic Implantable Collamer Lens implantation

Comparison of Accommodation and Accommodative Micro-Fluctuation After Implantable Collamer Lens and LASIK Surgery for Myopia

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