Dynamic Changes in Fibrinogen and Prognosis of Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis

Predictive value of D‐dimer/albumin ratio and fibrinogen/albumin ratio for in‐hospital mortality in patients with COVID‐19

“…Hyperfibrinogenemia increases the risk of coronary artery disease, deep vein thrombosis and ischemic stroke. [17][18][19] Although both D-dimer and fibrinogen are indicators of coagulation and inflammation, D-dimer was found to be more predictive of in-hospital mortality than fibrinogen (AUC of D-dimer and fibrinogen: 0.757, 0.637; odds ratio of D-dimer and fibrinogen: 6.058, 2.794). The reason of this is that while fibrinogen levels increase in the early stage of inflammation, they tend to peak and then decrease in the late stages when the disease is severe.…”

“…In December 2019, a disease of unknown aetiology emerged in Wuhan, China, with clinical symptoms of acute upper respiratory tract infection. 1 This disease, called coronovirus disease 2019 (COVID- 19), was evaluated in the pandemic category by the World Health Organisation (WHO) in January 2020. 2 According to WHO data, approximately 117 million people have been infected, whereas approximately 2.6 million people died.…”

Predictive value of d-dimer/albumin ratio and fibrinogen/albumin ratio for in-hospital mortality in patients with COVID-19

“…The reason for the relationship between high fibrinogen levels and COVID-19 mortality is hypercoagulation (16), which is also caused by high d-dimer levels. Hyperfibrinogenemia increases the risk of coronary artery disease, deep vein thrombosis, and ischemic stroke (17)(18)(19). Although both d-dimer and fibrinogen are indicators of coagulation and inflammation, d-dimer was found to be more predictive of in-hospital mortality than fibrinogen (AUC of d-dimer and fibrinogen: 0.757, 0.637; odds ratio of d-dimer and fibrinogen: 6.058, 2.794).…”

“…In December 2019, a disease of unknown etiology emerged in Wuhan, China, with clinical symptoms of acute upper respiratory tract infection (1). This disease, called coronovirus disease 2019 (COVID- 19), was evaluated in the pandemic category by the World Health Organization (WHO) in January 2020 (2). According to WHO data, approximately 117 million people have been infected, while approximately 2.6 million people died.…”

“…Introduction: Due to the high mortality of coronavirus disease 2019 (COVID- 19), there are difficulties in the managing emergency department. We investigated whether the d-dimer/albumin ratio (DAR) and fibrinogen/albumin ratio (FAR) predicts mortality in the COVID-19 patients.…”