Dynamic Exercise Leads to an Increase in Circulating ICAM-1: Further Evidence for Adrenergic Modulation of Cell Adhesion

Effects of laboratory versus field exercise on leukocyte subsets and cell adhesion molecule expression in children

“…Lymphocytes expressing CD54 [known also as intercellular adhesion molecule-1 (ICAM-1)] also increased in response to exercise in both protocols, a response similar to what has been observed previously in adults (Rehman et al 1997). The CD54 is an inducible cell adhesion glycoprotein expressed on the surface of a wide variety of cell types.…”

“…This study demonstrates that in children, like in adults, exercise, both ®eld and laboratory, in¯uences adhesion molecules (Rehman et al 1997;Miles et al 1998). The CD62L on circulating lymphocytes was decreased, and there was a preferential increase in CD62L ± versus CD62L + T-cell subsets.…”

Immobilization Stress Inhibits Intimal Fibromuscular Proliferation in the Process of Arterial Remodeling in Rats

“…They also increase blood pressure and heart rate, thereby increasing shear stress and producing endothelial damage. Adhesion molecules, including intercellular adhesion molecule-1 (ICAM-1) (28,29) and vascular cell adhesion molecule-1 (VCAM-1), are up-regulated (30)(31)(32). Circulating inflammatory cells (monocytes and lymphocytes) become able to bind to the surface of the endothelium and translocate into the subendothelial space.…”

Highly Sensitive Determination of Plasma Cytokines by Time-Resolved Fluoroimmunoassay; Effect of Bicycle Exercise on Plasma Level of Interleukin-1 (IL-1), Tumor Necrosis Factor a (TNF a), and Interferon γ (IFN γ)

“…The increase or decrease of cytokines is considered to correlate to the modulation of lymphocytes including NK cells via enhanced adhesion molecules. 24 On the other hand, it is considered that the modulation of NK-cell activity (NK cell cytotoxicity) or NK cell numbers, which is induced by exercise, stimulates the immune system or causes immune deficiency. 24 For the promotion of physical activities and public health, further research on the effect of exercises on the immune systems is necessary.…”

“…24 On the other hand, it is considered that the modulation of NK-cell activity (NK cell cytotoxicity) or NK cell numbers, which is induced by exercise, stimulates the immune system or causes immune deficiency. 24 For the promotion of physical activities and public health, further research on the effect of exercises on the immune systems is necessary. The assay of cytokines in plasma which affect immune systems should be of great help for these purposes.…”