Dynamic first pass 3D EPI of the prostate: accuracy in tumor location

Storaas, T.; Gjesdal, Kjell-Inge; Svindland, Aud; Viktil, Ellen; Geitung, Jonn Terje

doi:10.1080/00365520410009357

Cited by 7 publications

(2 citation statements)

References 18 publications

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“…The DCE imaging produced better agreement with biopsy and better inter-observer agreement than the T2-weighted images. Storaas et al (2004) also evaluated DCE MRI for prostate localization. Twenty-eight patients were imaged with gadolinium DCE T1-weighted 3D echo planar imaging and a T2-weighted turbo spin echo (TSE) sequence.…”

Section: Mri Contrast Enhanced Perfusion and Diffusion Imaging Mri Pe...mentioning

confidence: 99%

Anatomical imaging for radiotherapy

Evans¹

2008

Phys. Med. Biol.

110

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The goal of radiation therapy is to achieve maximal therapeutic benefit expressed in terms of a high probability of local control of disease with minimal side effects. Physically this often equates to the delivery of a high dose of radiation to the tumour or target region whilst maintaining an acceptably low dose to other tissues, particularly those adjacent to the target. Techniques such as intensity modulated radiotherapy (IMRT), stereotactic radiosurgery and computer planned brachytherapy provide the means to calculate the radiation dose delivery to achieve the desired dose distribution. Imaging is an essential tool in all state of the art planning and delivery techniques: (i) to enable planning of the desired treatment, (ii) to verify the treatment is delivered as planned and (iii) to follow-up treatment outcome to monitor that the treatment has had the desired effect. Clinical imaging techniques can be loosely classified into anatomic methods which measure the basic physical characteristics of tissue such as their density and biological imaging techniques which measure functional characteristics such as metabolism. In this review we consider anatomical imaging techniques. Biological imaging is considered in another article. Anatomical imaging is generally used for goals (i) and (ii) above. Computed tomography (CT) has been the mainstay of anatomical treatment planning for many years, enabling some delineation of soft tissue as well as radiation attenuation estimation for dose prediction. Magnetic resonance imaging is fast becoming widespread alongside CT, enabling superior soft-tissue visualization. Traditionally scanning for treatment planning has relied on the use of a single snapshot scan. Recent years have seen the development of techniques such as 4D CT and adaptive radiotherapy (ART). In 4D CT raw data are encoded with phase information and reconstructed to yield a set of scans detailing motion through the breathing, or cardiac, cycle. In ART a set of scans is taken on different days. Both allow planning to account for variability intrinsic to the patient. Treatment verification has been carried out using a variety of technologies including: MV portal imaging, kV portal/fluoroscopy, MVCT, conebeam kVCT, ultrasound and optical surface imaging. The various methods have their pros and cons. The four x-ray methods involve an extra radiation dose to normal tissue. The portal methods may not generally be used to visualize soft tissue, consequently they are often used in conjunction with implanted fiducial markers. The two CT-based methods allow measurement of inter-fraction variation only. Ultrasound allows soft-tissue measurement with zero dose but requires skilled interpretation, and there is evidence of systematic differences between ultrasound and other data sources, perhaps due to the effects of the probe pressure. Optical imaging also involves zero dose but requires good correlation between the target and the external measurement and thus is often used in conjunction with an x-ray method. The use of an...

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Section: Mri Contrast Enhanced Perfusion and Diffusion Imaging Mri Pe...mentioning

confidence: 99%

Anatomical imaging for radiotherapy

Evans¹

2008

Phys. Med. Biol.

110

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“…The role of DCE MRI in the detection of prostate cancer has been much discussed. A paper published in 2004 concluded that "DCE 3D EPI did not improve tumor location compared with that of T2 W TSE images" (148). The value of DCE MRI in prostate cancer was also reviewed in 2008 (149).…”

Section: Perfusion Imaging With Contrast Mediamentioning

confidence: 99%

The history of magnetic resonance imaging and its reflections in Acta Radiologica

Smith

2021

Acta Radiol

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The first reports in Acta Radiologica on magnetic resonance imaging (MRI) were published in 1984, four years after the first commercial MR scanners became available. For the first two years, all MR papers originated from the USA. Nordic contributions started in 1986, and until 2020, authors from 44 different countries have published MR papers in Acta Radiologica. Papers on MRI have constituted, on average, 30%–40% of all published original articles in Acta Radiologica, with a high of 49% in 2019. The MR papers published since 1984 document tremendous progress in several areas such as magnet and coil design, motion compensation techniques, faster image acquisitions, new image contrast, contrast-enhanced MRI, functional MRI, and image analysis. In this historical review, all of these aspects of MRI are discussed and related to Acta Radiologica papers.

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Transrectal ultrasound‐guided biopsy of prostate voxels identified as suspicious of malignancy on three‐dimensional ¹H MR spectroscopic imaging in patients with abnormal digital rectal examination or raised prostate specific antigen level of 4–10 ng/ml

et al. 2006

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Results of the evaluation of transrectal ultrasound (TRUS) guided needle biopsy of voxels identified as suspicious of malignancy on magnetic resonance spectroscopic imaging (MRSI) in a large cohort of men (n = 83) with abnormal digital rectal examination (DRE) [prostate specific antigen (PSA) 0-4 ng/ml] or PSA less than 10 ng/ml, are reported. Three-dimensional (1)H MRSI was carried out at 1.5 T using a pelvic-phased array coil in combination with an endorectal surface coil. Voxels were classified as suspicious of malignancy based on Cit/(Cho + Cr) metabolite ratio. TRUS-guided biopsy of suspicious voxels was performed using the z- and x-coordinates obtained from MR images and two to three cores were taken from the suspected site. A systematic sextant biopsy was also carried out. MRSI showed voxels suspicious of malignancy in 44 patients while biopsy revealed cancer in 11 patients (25%). Patients who were negative for malignancy on MRSI were also negative on biopsy. An overall sensitivity of 100%, specificity of 54%, negative predictive value of 100% and accuracy of 60% were obtained. The site of biopsy was confirmed (n = 20) as a hypo-intense area on repeat MRI while repeat MRSI revealed high choline and low citrate. The overall success rate of MRI-directed TRUS-guided biopsy of 25% was higher compared with a 9% success rate achieved without MR guidance in another group of 120 patients. Our results indicate that TRUS-guided biopsy of suspicious area identified as malignant from MRSI can be performed using the coordinates of the voxel derived from MR images. This increases the detection rate of prostate cancer in men with PSA level <10 ng/ml or abnormal DRE and also demonstrates the potential of MR in routine clinical practice.

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Dynamic first pass 3D EPI of the prostate: accuracy in tumor location

Abstract: DCE 3D EPI did not improve tumor location compared with that of T2W TSE images. Further investigation is needed on how best to exploit the DCE technique.

Cited by 7 publications

References 18 publications

Anatomical imaging for radiotherapy

Anatomical imaging for radiotherapy

The history of magnetic resonance imaging and its reflections in Acta Radiologica

Transrectal ultrasound‐guided biopsy of prostate voxels identified as suspicious of malignancy on three‐dimensional ¹H MR spectroscopic imaging in patients with abnormal digital rectal examination or raised prostate specific antigen level of 4–10 ng/ml

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Dynamic first pass 3D EPI of the prostate: accuracy in tumor location

Abstract: DCE 3D EPI did not improve tumor location compared with that of T2W TSE images. Further investigation is needed on how best to exploit the DCE technique.

Cited by 7 publications

References 18 publications

Anatomical imaging for radiotherapy

Anatomical imaging for radiotherapy

The history of magnetic resonance imaging and its reflections in Acta Radiologica

Transrectal ultrasound‐guided biopsy of prostate voxels identified as suspicious of malignancy on three‐dimensional 1H MR spectroscopic imaging in patients with abnormal digital rectal examination or raised prostate specific antigen level of 4–10 ng/ml

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Transrectal ultrasound‐guided biopsy of prostate voxels identified as suspicious of malignancy on three‐dimensional ¹H MR spectroscopic imaging in patients with abnormal digital rectal examination or raised prostate specific antigen level of 4–10 ng/ml