“…Presurgical orthopedic appliances provide new options. Previous studies documented that presurgical nasoalveolar molding (PNAM) treatment can elongate the columella, retract the premaxilla, narrow cleft width, and improve nasolabial symmetry (Cutting et al, 1998;Grayson et al, 1999;Grayson and Cutting, 2001;Spengler et al, 2006;Liou et al, 2007;Aminpour and Tollefson, 2008;Lee et al, 2008) but its effect is limited (Hotz et al, 1987;Grayson et al, 1993;Bennun et al, 1999;Grayson et al, 1999;Grayson and Cutting, 2001;Liou et al, 2004;Grayson and Maull, 2005;Bennun and Figueroa, 2006). The centralization and retraction of the premaxilla are among the most difficult corrections to achieve.…”