Dynamical analysis of tumor model with obesity and immunosuppression

Abd-Rabo, Mahmoud A.; Zakarya, Mohammed; Alderremy, A. A.; Aly, Shaban

doi:10.1016/j.aej.2022.04.014

Cited by 2 publications

(3 citation statements)

References 36 publications

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“…It also suppresses the immune system. 92.72% of the participants in our study stated that they pay attention to their weight[31][32][33].…”

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confidence: 75%

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Changing Health Lifestyles After the Pandemic

Akarsu

2022

BJSTR

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Aim: Identifying lifestyles that have been changed to prevent disease during the COVID 19 pandemic. Materials and Methods:This cross-sectional study was conducted in the Central Anatolian region of Turkey. With the data collection form prepared by the researcher, open-ended questions were directed to the participants. The received answers were put into the form.Results: Of the participants, 56.02% were women, 84.87% lived in the city, 94.11% were single, and 2.24% had a chronic disease. BMI of 91.59% is in the range of 18-25. 33.05% still use masks, 35.57% now sleep early, 50.14% take a walk every day, 70.31% pay attention to regular water consumption. Conclusion:With the information obtained from the results of the study, the necessity of ventilation of the living environment and the power of mask and hand hygiene in preventing contamination became more understandable by people. Learning about the measures taken during pandemics in a region or community taken will cause us to be less affected by similar situations that may occur in the future, even if it is undesirable.

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“…It also suppresses the immune system. 92.72% of the participants in our study stated that they pay attention to their weight[31][32][33].…”

mentioning

confidence: 75%

“…for a short time by using other protective equipment and to understand the necessity of leaving these places. The rate of those using masks is33.05%. Bravo-Cucci et al (2022) stated in their study that 90.4% of the masks were used during the 1st spreading wave of COVID 19.…”

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confidence: 96%

Changing Health Lifestyles After the Pandemic

Akarsu

2022

BJSTR

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“…Consequently, it becomes impossible to predict the number of healthy host, tumor, and effector cells [11]. Another investigation [12] was made to examine the tumor cells' characteristics when the immune response is absent, wherein the tumor, normal, and fat cells were inspected using bifurcation in order to identify the chaotic regime. The findings exhibited the occurrence of codimention-1 bifurcation of the system and the complete absence of any periodic solutions.…”

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confidence: 99%

Role of Glucose Risk Factors on Human Breast Cancer: A Nonlinear Dynamical Model Evaluation

2022

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Understanding of the glucose risk factors-mediated mechanism in human breast cancer remains challenging. In this perception, for the first time, we proposed a complex nonlinear dynamical model that may provide a basic insight into the mechanism of breast cancer for the patient with existing glucose risk factors. The impact of glucose risk factors on the cancer cells’ population is evaluated using the formulated analytical model. The dynamical features of the cancer cells are described by a system of ordinary differential equations. Furthermore, the Routh–Hurwitz stability criterion is used to analyze the dynamical equilibrium of the cells’ population. The occurrence of zero bifurcation as well as two and three of the Jacobian matrix are obtained based on the sums of principal minors of order one. The glucose risk factors are exploited as the bifurcation parameters (acted as necessary and sufficient conditions) to detect the Hopf bifurcation. The presence of excess glucose in the body is found to affect negatively the breast cancer cells’ dynamics, stimulating chaos in the normal and tumor cells and thus drastically deteriorating the efficiency of the human immune system. The theoretical results are validated using the numerical simulations. It is concluded that the present findings may be beneficial for the future breast cancer therapeutic drug delivery and cure.

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Dynamical analysis of tumor model with obesity and immunosuppression

Cited by 2 publications

References 36 publications

Changing Health Lifestyles After the Pandemic

Changing Health Lifestyles After the Pandemic

Role of Glucose Risk Factors on Human Breast Cancer: A Nonlinear Dynamical Model Evaluation

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