A natural atom placed into a cavity with time-dependent parameters can be parametrically excited due to the interaction with the quantized photon mode. One of the channels of such a process is the dynamical Lamb effect, induced by a nonadiabatic modulation of atomic level Lamb shift. However, in experiments with natural atoms it is quite difficult to isolate this effect from other mechanisms of atom excitation. We point out that a transmission line cavity coupled with a superconducting qubit (artificial macroscopic atom) provides a unique platform for the observation of the dynamical Lamb effect. A key idea is to exploit a dynamically tunable qubit-resonator coupling, which was implemented quite recently. By varying nonadiabatically the coupling, it is possible to parametrically excite a qubit through a nonadiabatic modulation of the Lamb shift, even if the cavity was initially empty. A dynamics of such a coupled system is studied within the Rabi model with timedependent coupling constant and beyond the rotating wave approximation. An efficient method to increase the effect through the periodic and nonadiabatic switching of a qubit-resonator coupling energy is proposed.Superconducting circuits with Josephson junctions can be used for quantum computing as qubits. They can be integrated with microwave waveguides, while the photon field in these waveguides is quantized. A well known Rabi model is applicable for the description of qubit-photon quantum system.Moreover, superconducting circuits integrated with microwave resonators provide a unique platform for an observation of cavity quantum electrodynamical (QED) nonstationary phenomena which can hardly be studied in more traditional experiments. One of the examples of such nonstationary QED phenomena is the dynamical Casimir effect. It is remarkable that it was a superconducting system, which led to the first observation of the dynamical Casimir effect [1,2].A presence of an additional atom in a cavity with time-dependent parameters leads to other nonstationary QED phenomena. For instance, an atom can be parametrically excited, even if the cavity was initially empty. In the case of a nonadiabatical modulation of cavity parameters, there are a Corresponding author: lozovik@isan.troitsk.ru