Dynamics and Infradian Rhythmics of Thermal/Pain Sensitivity of the Helix Mollusc under the Action of Electromagnetic Fields

Abstract

We measured characteristics of thermal/pain (th/p) sensitivity of Helix albescens (threshold and latency of the avoidance behavioral reaction) under conditions of the hot-plate test. As was found, weakening (shielding) of the background electromagnetic field, as well as the action of low-intensity radiations of extremalfrequency ranges, induced two-phase changes of these characteristics within a 21-day-long observation period with different manifestations and durations of the phases. Initial increase in the nociceptive sensitivity (hyperalgesia) was followed by an analgesic effect with subsequent return of the examined indices to the initial level. Low-intensity electromagnetic influences also induced modifications of the infradian rhythmics of th/p sensitivity of the molluscs; this was manifested in changes of the spectra and phase shifts of the identified rhythms and trends toward modulation of the amplitudes of these rhythmic components.

Role of the Opioid System in the Modulation of Thermonociceptive Sensitivity of Mollusks Affected by Weak Electromagnetic Factors

“…In the case of the action of low-frequency OMF, the 1st (hyperalgesic) phase was mild and short (about 3 days); in contrast, the subsequent hypoalgesic effect was much more intense and long-lasting (its duration exceeded the observation period in our experiments). In general, results of the present experiments agree rather well with the data obtained in our preceding work [1].…”

“…Earlier, we observed complex multiphase changes in thermonociceptive sensitivity of terrestrial pulmonary mollusks, Helix albestens, which were manifested under conditions of shielding from background electromagnetic fields (EMFs) and action of weak oscillating magnetic fields (OMFs) of an extremely low-frequency (ELF) range [1]. It should, however, be recognized that elucidation of the mechanisms responsible for changes in the thermonociceptive sensitivity under the action of the above factors and also of EMFs with other characteristics remains in the initial stages.…”

A biopolymer-gated ionotronic junctionless oxide transistor array for spatiotemporal pain-perception emulation in nociceptor network

“…S4 (ESI). † 45,53 The corresponding results are further summarized in Table S3 (ESI). † Compared with other tissues, the skin is more densely dominated by nociceptors, and they are widely distributed in the dermis of the skin.…”

Biological effects of the hypomagnetic field: An analytical review of experiments and theories

“…Each work reviewed is unique and, therefore, not replicated by an independent scientific group. Rare exclusion is HMF nociception studies reported in [ 71 , 81 , 92 , 97 ] and [ 112 , 114 , 132 , 152 ]. Non-reproducibility is a common problem in laboratory magnetobiology.…”