Dynamics of Fluorescence Quenching of Pyrene in Novel Micelles of the Zwitterionic Betaine SurfactantN-(3-Dodecyloxy-2-hydroxypropyl)-N,N-dimethylglycine

Guan, Jing‐Qu; Tung, Chen‐Ho

doi:10.1006/jcis.1998.5754

Cited by 8 publications

(7 citation statements)

References 36 publications

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“…The emulsifying potential of DMG has also been described in different contexts (Cools et al 2010;Kalmar et al 2010a, b;Guan and Tung 1998). Kalmar et al (2010a) added DMG to a water-oil mixture and observed a stable emulsion.…”

Section: Discussionmentioning

confidence: 91%

“…The effects on nutrient digestibility are suggested to result from an emulsifying action at the gut level. Both DMG and betaine derived molecules are used as surfactants in industrial applications (Guan and Tung 1998;Clapés and Infante 2002). Enhanced emulsification of dietary fat by use of additives with surfactant properties Electronic supplementary material The online version of this article (doi:10.1007/s00726-011-1068-y) contains supplementary material, which is available to authorized users.…”

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confidence: 99%

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Glycine and its N-methylated analogues cause pH-dependent membrane damage to enterotoxigenic Escherichia coli

Vanhauteghem

Janssens

Lauwaerts³

et al. 2011

Amino Acids

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The current study first investigates the emulsifying potential of glycine and its N-methylated derivatives N-methylglycine (sarcosine), N,N-dimethylglycine (DMG) and N,N,N-trimethylglycine (betaine) under varying pH conditions. Subsequently, the effect of these test compounds on the membrane integrity of enterotoxigenic Escherichia coli (ETEC) was evaluated. Oil in water emulsions containing each compound show that DMG is a more potent enhancer of emulsification than glycine, sarcosine and betaine under the conditions tested. Flow cytometry was used to investigate whether the emulsifying potential is associated with an effect on ETEC membrane integrity. The bacteria were exposed to each of the test compounds under varying pH conditions and membrane integrity was assessed using the LIVE/DEAD BacLight kit. Results show a membrane deteriorating effect caused by glycine, sarcosine and DMG, but not by betaine. This effect is pH- and time-dependent and has an apparent threshold at pH 9.0. Conventional plate counts confirmed concomitant changes in culturability of the membrane comprised bacteria.

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Section: Discussionmentioning

confidence: 91%

mentioning

confidence: 99%

Glycine and its N-methylated analogues cause pH-dependent membrane damage to enterotoxigenic Escherichia coli

Vanhauteghem

Janssens

Lauwaerts³

et al. 2011

Amino Acids

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“…Among all amphoteric surfactants, betaine structures is very effective for metallic complexation and oil dispersion (Kudaibergenov 2002). The use of N-(3-Dodécyloxy-2-hydroxypropyl)-N,N-diméthylgly-cine (DHDG) for pyrene has been shown possible (Guan and Tung 1998).…”

Section: Introductionmentioning

confidence: 99%

Amphoteric Surfactants for PAH and Lead Polluted-Soil Treatment Using Flotation

Mouton

Mercier

Blais

2008

Water Air Soil Pollut

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Polluted soils are a problem of major concern impacting the health of the global environment and human beings. Without any safe technology for polluted soil treatment, most of the contaminated soils go to landfill especially when metals are the pollutants. This research compares the performance of non ionic (Brij 35 and Tween 80) and amphoteric (cocamydopropyl hydroxysultaine (CAS) and coamydopropylbetaine (BW)) surfactants for polycyclic aromatic hydrocarbons (PAHs) and metals (mainly Pb) removal from three contaminated soils. Best removal yields have been obtained using 0.5% (w/w) of CAS surfactant with 46± 2% for PAHs and 21±5% for Pb simultaneously removed. Sodium chloride and EDTA have been shown to considerably enhance Pb solubilization (respectively 55±5% and 35±12% for [NaCl]=5.5 M and [EDTA]=0.025 M). Flotation technology has been tested as a separating technique of PAHs micelles and Pb from aqueous solution and has given good results for both contaminants (54±7% for both PAH and Pb, using [CAS]=0.5%, [NaCl]=5.5 M, pH=3). Finally, this study proposes a soil washing process using flotation to treat soil polluted with both organic and inorganic compounds. The suggested process concentrates the organic compounds in the froth and the inorganic pollutants in the liquid fraction.

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“…In that study, an improved feed conversion rate of DMG-supplemented broilers was reported. Besides the application of DMG as a supplement for both humans and animals, DMG-derived molecules are also used as surfactants in industrial applications (Guan and Tung, 1998), which indicates that DMG can possibly function as an emulsifying agent when added to the feed.…”

Section: Introductionmentioning

confidence: 99%

Effect of N,N-dimethylglycine supplementation in parturition feed for sows on metabolism, nutrient digestibility and reproductive performance

Cools

Maes

Buyse

et al. 2010

Animal

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The current pilot study assessed the influence of N,N-dimethylglycine (DMG) on insulin sensitivity, glucose and fat metabolism, nutrient digestibility and reproductive performance of sows in the peripartal period. At day 105 of gestation, 25 sows were randomly assigned to the control (n 5 13) or the DMG group (n 5 12). Sows from the DMG group were supplemented with 1 g DMG/kg feed until day 3 of lactation. After an overnight fast 1 day after farrowing, a blood sample of each sow was drawn. The plasma was analyzed for insulin, glucose, fructosamine, leptin, thiobarbituric acid reactive substances (TBARS), ferric reducing ability of plasma (FRAP), non-esterified fatty acids (NEFA) and triglycerides (TG) and an oral glucose tolerance test was performed. A rectal feces sample was collected and the apparent fecal digestibility (AFD) of crude fat (CFAT), crude protein (CP) and nitrogenfree extract (NFE) was calculated after proximate analyses. Finally, a colostrum sample was collected from each sow and analyzed for the presence of DMG. Reproductive performance parameters were recorded. The results showed an improvement in the AFD of CFAT, CP and NFE when DMG was supplemented. This beneficial effect confirms the hypothesis that DMG acts as an emulsifying agent. The improvement in digestibility in the DMG group was accompanied by a numerical increase in plasma TG (P 5 0.067). Plasma NEFA concentrations were not different between treatment groups. DMG supplementation neither affected glucose clearance nor influenced plasma insulin, glucose, fructosamine or leptin levels. TBARS and FRAP also remained unaffected, despite previously reported anti-oxidative properties of DMG. Furthermore, no significant impact on reproductive performance could be recorded. In conclusion, DMG supplementation significantly improved nutrient digestibility. Possible beneficial effects on energy metabolism and reproductive performance of sows should be tested when DMG is supplemented for a longer period of time or at a higher dose.Keywords: sow, N,N-dimethylglycine, nutrient digestibility, glucose metabolism, reproduction ImplicationsThe supplementation of N,N-dimethylglycine (DMG) in parturition feed of sows has an emulsifying effect. This resulted in improvements in not only fat digestibility, but also the digestibility of the protein and the nitrogen-free dietary fraction. However, measures of reproductive performance were not affected by DMG supplementation. The addition of this supplement to gestation and lactation feed should be investigated. Supplementation of DMG over a longer period of time can possibly be beneficial in terms of sow body condition and reproductive performance of sows.

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Dynamics of Fluorescence Quenching of Pyrene in Novel Micelles of the Zwitterionic Betaine SurfactantN-(3-Dodecyloxy-2-hydroxypropyl)-N,N-dimethylglycine

Cited by 8 publications

References 36 publications

Glycine and its N-methylated analogues cause pH-dependent membrane damage to enterotoxigenic Escherichia coli

Glycine and its N-methylated analogues cause pH-dependent membrane damage to enterotoxigenic Escherichia coli

Amphoteric Surfactants for PAH and Lead Polluted-Soil Treatment Using Flotation

Effect of N,N-dimethylglycine supplementation in parturition feed for sows on metabolism, nutrient digestibility and reproductive performance

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