2020
DOI: 10.17116/stomat20209906113
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Dynamics of immune and biochemical features of oral fluid in persons with caries receiving vitamin D

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“…When the concentration of the vitamin D biomarker 25(OH)D3 in serum was lower than 30 ng/mL in patients with dental caries, the levels of secretory immunoglobulin A (sIgA), LPS binding protein (LBP), cathelicidin and total antioxidant activity decreased. After VD supplementation (VDS), the levels returned to normal [ 20 ], and saliva LL-37 levels was related to serum concentration of vitamin D in six-year-old children [ 21 ]. These results demonstrate the important role of 1,25D3-induced AMPs, suggesting a potential association between VD deficiency and susceptibility to microbial infections.…”
Section: Protective Action Of 125d3 Against Periodontitismentioning
confidence: 99%
“…When the concentration of the vitamin D biomarker 25(OH)D3 in serum was lower than 30 ng/mL in patients with dental caries, the levels of secretory immunoglobulin A (sIgA), LPS binding protein (LBP), cathelicidin and total antioxidant activity decreased. After VD supplementation (VDS), the levels returned to normal [ 20 ], and saliva LL-37 levels was related to serum concentration of vitamin D in six-year-old children [ 21 ]. These results demonstrate the important role of 1,25D3-induced AMPs, suggesting a potential association between VD deficiency and susceptibility to microbial infections.…”
Section: Protective Action Of 125d3 Against Periodontitismentioning
confidence: 99%